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Automation – Multimedia

App Note / Case Study

Purification of Genomic DNA from Saliva Using Oragene® Discover Collection Kits and the Akonni TruTip® Extraction System on the Hamilton Microlab® STAR Liquid Handling Workstation

In the following studies, we have demonstrated the high precision of the automated TruTip extraction technology in processing genomic DNA from low-volume saliva samples and its advantage over competitors.
App Note / Case Study

Rapid, High Throughput Extraction and Purification of Genomic DNA from Whole Blood Using the Akonni TruTip® Extraction System on the Hamilton Microlab® STAR Liquid Handling System

This application note demonstrates the high precision of the automated extraction system in processing genomic DNA from low volume whole blood samples and its advantage over competitors.
App Note / Case Study

Next Generation Sequencing Method for Illumina TruSeq DNA Sample Preparation Protocol on the Hamilton STAR

The purpose of the TruSeq sample preparation protocol is to add adapter sequences onto the ends of DNA fragments to generate multiplexed sequencing libraries. Good liquid handling is crucial for pipetting precise volumes for example for Agilent Bioanalyzer.
App Note / Case Study

Automated GS FLX Titanium emPCR Enrichment using the REM e System on a Hamilton Microlab® STARlet Liquid Handler

The Genome Sequencer FLX System is a versatile sequencing platform suitable for a wide range of research applications, including de novo sequencing and assembly of genomic DNA, transcriptome sequencing, small RNA analysis, and amplicon sequencing.
App Note / Case Study

Automated Liquid-liquid Extraction of 25-Hydroxy Vitamin D from Serum and Preparation for LC/MC Analysis Using the Hamilton Robotics Microlab STARlet Workstation

This application note demonstrates the automation capabilities of Hamilton Robotics’ Microlab STARlet and how it can be used to prepare clinical serum samples for Vitamin D analysis quickly, reliably and cost effectively.
App Note / Case Study

Fully Automated 24-Well Madin-Darby Canine Kidney (MDCK) Permeability Assay Utilizing the Hamilton Microlab® Star Liquid Handling Platform

We have successfully developed a fully automated protocol utilizing a Hamilton MICROLAB STAR integrated with select third party peripheral devices to suit the assay requirements. The method was validated using 23 marketed drugs with diverse physico-chemical properties and a wide range of published apparent permeabilities (Papp).
App Note / Case Study

Tryptic Mapping Automated on the CyBi®-RoboSpense and Integration of an Agilent 1100/1200 HPLC System for Peptide Analysis

This application note describes automation of the tryptic mapping process on the CyBi®-RoboSpense liquid handling platform. The automation is completed through integrating an Agilent 1100/1200 HPLC system.
App Note / Case Study

Nanoliter Scale High-Throughput Protein Crystallography Screening with the Echo Liquid Handler

The Echo® liquid handler enables protein crystal formation with sitting drop volumes as small as 50 nL. Nanoliter volumes of protein and crystallography reagents can be transferred into sitting drop wells of crystallography plates. Precise and accurate drop placement eliminates cross-contamination and ensures drop-on-drop placement for blending protein and crystallography solutions.
App Note / Case Study

Determination of Antioxidant potential using an Oxygen Radical Absorbance Capacity (ORAC) Assay with Synergy™ H4

The oxygen radical absorbance capacity (ORAC) assay has emerged as a robust analytical method to determine the antioxidant potential of a range of substances found in neutraceutical, pharmaceutical and food products. This application note demonstrates the ability to perform the assay in a 96-well microplate format amenable to higher throughput platforms.
Development of an Automated Platform for HT Cloning and Expression content piece image
Poster

Development of an Automated Platform for HT Cloning and Expression

Biomolecular protocols covering the whole cloning process were implemented in liquid handler robots. When compared to the manual approach, it was found that automation significantly speeds up HT cloning.
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