Cell Culture – News and Features

Researchers have identified a way to rapidly proliferate hepatocyte organoids that mimic the metabolic complexity of the liver.

New research demonstrates the role of the Galectin-1 protein in the nucleus of the cells surrounding the tumor-fibroblasts contributing to their activation.

A study by Kindai University researchers shows that neurons adapt their migration strategies based on environmental conditions. Using PIEZO1, a mechanosensitive ion channel, neurons can adjust their movement in confined 3D environments.

NTNU researchers identified an oral antiviral cocktail that blocks enterovirus replication in human cells and mini-organs. The combination, previously tested for safety, showed no adverse effects on heart or pancreatic function.

Learn about Colossal's dire wolf de-extinction breakthrough and how this technology could reshape conservation.

The FDA has announced plans to replace animal testing for many drugs in favor of AI and human-based lab models. The new approach is designed to improve drug safety and accelerate the evaluation process, while reducing animal experimentation.

Drug discovery efforts have expanded beyond the traditional approaches of small molecules and antibodies to include cells. This article explores the use of microfluidic methods for high-throughput screening of cell-based drug products.

Three-dimensional models allow researchers to better represent complex tissues and cell-cell interactions. This article explores the cell models currently used by researchers to understand disease and aid drug discovery.

Researchers discuss how organoids and organ-on-a-chip technologies are transforming women’s health research. By mimicking female-specific tissues, these models uncover new insights into diseases that affect women, such as breast cancer.

A recent study found that placenta-derived IL1α under hypoxic conditions, can greatly increase growth of human stem cell-derived liver organoids. This method offers a promising route to improve organoid models and regenerative medicine.