Cell Signaling – News and Features

Biological condensates that form "blobs" in cells have a greater effect on cellular biochemistry than previously thought, including providing an alternative energy source.

Lab-grown blood stem cells could benefit from having inflammatory signals switched off, a new study reveals.

A recent study highlights the role of sphingolipids in cancer cells' immune evasion strategies. Researchers found that these lipids, crucial for cell membrane stability, help tumors avoid immune detection.

Research suggests that low doses of carbon monoxide, similar to levels in smokers, may protect against Parkinson’s disease. The findings highlight potential pathways for new Parkinson’s treatments and warrant further clinical trials.

Researchers at the University of Alabama at Birmingham discovered that combining regorafenib with a dual JAK/HDAC inhibitor significantly improves treatment efficacy for metastatic colorectal cancer while minimizing toxic side effects.

A new study has created the most detailed human endometrial map, revealing unique cell types and interactions throughout the menstrual cycle. This atlas could advance understanding of endometriosis and hormone-related conditions.

Researchers have discovered a pathway where immune cells and sensory nerves interact to cause itching and allergic reactions. The study suggests new potential treatments for allergies and chronic itchiness.

A study reveals how sex hormones, such as testosterone and estrogen, regulate immune system functions. Analyzing hormone therapy effects in transgender men, researchers identified changes in immune signaling pathways.

Researchers have uncovered that the protein PRDM1-S disrupts immune regulation in multiple sclerosis and other autoimmune diseases by increasing the enzyme SGK-1. This finding provides insight into the molecular mechanisms behind these conditions.

A study of over 72,000 patients found that obese individuals are 34% more likely to contract COVID-19 than non-obese peers. This increased susceptibility underscores obesity as a significant risk factor for both infection and transmission.