Drug Targets – Multimedia

One of the common molecular analyses is the determination of a lead molecule’s binding kinetics and affinity to the target. This warrants the need for analytical instruments capable of characterizing such molecules. Download this whitepaper to discover an approach that accurately measures multiple high-affinity interactions over long run times.

Download this app note to discover more about binding parameters and high-throughput assays in drug development.

Immunoprecipitation in its basic form is very simple, however protein–protein binding often involves transient and weak interactions. It is therefore paramount to use a method that offers rapid binding kinetics and low nonspecific binding.

Scripps Research chemist Matthew Disney, Ph.D., and colleagues have created drug-like compounds that, in human cell studies, bind and destroy the pandemic coronavirus’ so-called “frameshifting element” to stop the virus from replicating.

Access this whitepaper to discover how the analytical techniques that can facilitate research, development and quality control during drug development.

Download this app note to discover how applying the XF Substrate Oxidation Stress Test can determine which substrates are relevant or required for specific cellular functions or phenotypes.

In this eBook we delve deeper into the topic of drug pharmacology – focusing on drug kinetics, medicinal chemistry and pharmacokinetics.

Download this guide to explore how the genes, proteins and pathways modulating energy metabolism represent a promising new avenue for developing novel therapeutic strategies capable of tackling a broad range of diseases.

In this app note, discover a method for analyzing binding kinetics that is high resolution, high throughput and non-radioactive

Each year, Nobel Prizes are awarded to people who have made a significant contribution in their field; this list focuses on the Nobel Prizes awarded between 2010 and 2019 to those “who made the most important discovery within the domain of physiology or medicine”.