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Neurogenomics – News and Features

A girl sat alone in a room looking out a window.

Study Identifies Genetic Roots of PTSD

Findings from the largest genetic study of PTSD to date could help explain why only some people develop the condition after experiencing trauma.
High magnification micrograph of microglia cells stained with Rio-Hortega's method (silver carbonate). This type is the ramified or resting microglia that appears in normal brain tissue.

Mobilizing Microglia in the Fight Against Alzheimer’s Disease

Recently approved Alzheimer's drugs work by tagging amyloid plaques for clearance by the brain's microglia. Washington University School of Medicine in St. Louis researchers are developing an alternative approach, using a homemade antibody to directly mobilize microglia.
A scientist in a white lab coat helps a person with Down syndrome into a brain scan machine.

Alzheimer’s Starts Earlier and Progresses Faster in People With Down Syndrome

A new study revealed that Alzheimer's disease starts earlier and progresses faster in people with Down syndrome, which could have important implications for their treatment and care.
Brain cells under a microscope.

Lewy Bodies in Brain Cells Reveal Parkinson’s Disease Insights

A new study from Van Andel Institute scientists offers a first look into the complex molecular changes that occur in brain cells with Lewy bodies, which are key pathological hallmarks of Parkinson’s disease and some dementias.
Double helix structure of DNA.

Single-Cell Atlas Sheds Light on Pristina leidyi's Regenerative Capabilities

An international team of scientists has published the first single-cell atlas forPristina leidyi (Pristina), a segmented annelid with extraordinary regenerative abilities that has fascinated biologists for more than a century.
Vitamin A-containing foods.

Vitamin A and Human Health: What’s the Latest Research?

Here, we highlight some of the latest advancements in vitamin A research working to address its effects on human health.
Two hands reaching out to one another.

Is Left-Handedness Tied to Your Genetics? Possibly, New Study Suggests

Why are some people right-handed, while others are left-handed? A new study has found left-handed people carry a specific genetic variation at a higher rate than righties.
A portrait of a woman moving her head and screaming.

Filtering and Predictive Issues in the Brain Are Linked to Psychosis

Inside the brains of people with psychosis, two key systems are malfunctioning: a “filter” that directs attention toward important events and thoughts, and a “predictor” composed of pathways that anticipate rewards.
A 3D model of a human brain.

A New Genetic Variant That Protects Against Alzheimer’s

Columbia researchers have discovered a genetic variant that reduces the odds of developing Alzheimer’s disease by up to 70% and may be protecting thousands of people in the United States from the disease.
Olive oil next to a plant on a table.

Potential Therapy Identified for Gene Mutation Associated With Increased Viral Infection Susceptibility

A gene mutation associated with a rare neurological disorder and increased susceptibility to viral infections may be treatable with oleic acid.