Neurogenomics – News and Features

Disrupting the body’s internal clock during adolescence can alter how the brain responds to an in-utero risk factor linked to certain brain disorders, a new mouse study suggests.

Single-cell analysis of brain tissue has revealed genome alterations linked to PTSD, offering insights into targeted treatments.

The study reveals a significant relationship between elevated iron levels in the brain and greater cellular damage in individuals with both Down syndrome and Alzheimer’s disease.

Transplanting healthy human glial progenitor cells into the brains of adult animal Huntington's disease models not only slowed motor and cognitive decline but also extended lifespan.

A study shows how a class of drugs, HDACi (histone deacetylase inhibitors), protects neurons and limits brain damage following stroke by altering the gene expression of microglia, the immune cells of the brain.

This article explores how next-generation sequencing has revolutionized microbiome research, enabling comprehensive analysis of microbial communities and their roles in health and disease.

Circular RNAs are crucial for development, thought and synaptic function, yet their high prevalence in neurons has long been a scientific mystery.

Researchers have discovered that the glycoprotein reelin is a marker for cocaine-activated neurons in the nucleus accumbens. Reelin plays a key role in cocaine-related gene expression, neuron excitability and behavior changes.

A stem cell platform aims to recreate the brain's immune system using lab-grown human microglia cells, to understand how it functions – and fails – in neurodegenerative disease.

Researchers at Charité - Universitätsmedizin Berlin look for new cancer diagnostic procedures. The result is an AI model that makes use of the specific characteristics in the genetic material of tumors.