Fragment-based Approach to Multi-target Compounds
The presented work deals with the development of a fragment based strategy for dual-target drug discovery.
Tissue and cfDNA Rare Alleles How Low Can We Go
Seth Crosby, Washington University School of Medicine, discusses both bench and informatic methods used to increase specificity in the apprehension of rare cfDNA alleles.
Characterising Plant Genomes The Good The Bad and The Ugly
Next generation DNA sequencing has revolutionised biology. However, the low cost and relative ease in generating draft genome assemblies has led to the production of many genome sequences of questionable quality or applicability.
Knowledge-Based Identification of Plant Stress Regulators
As currently applied, digital PCR can only be used to detect known mutations at single sequence positions, for 'hotspot' mutations.