Defective Glial Cells Can Push Neurons Toward Parkinson's DiseaseNews
Scientists have discovered that defective astrocytes are linked to the buildup of a toxic protein that is one the hallmarks of Parkinson's disease. The studied astrocytes, derived from Parkinson's disease patients with a genetic mutation that affects cell clean-up functions, caused more accumulation of the toxin, α -synuclein, than those derived from healthy individuals.Read more
Interference with Estrogen Signaling Sends Bone Formation into OverdriveNews
Deleting a certain type of estrogen receptor in an area of the hypothalamus dramatically increased bone density and strength in female mice, opening up many therapeutic possibilities for improving women's health.Read more
Now Anyone Can Tour the Fly BrainNews
A new fly-through of the fly brain allows anyone to whizz past neurons and visit any of the 40 million synapses where neurons touch neuron. It’s a super-resolution view of the complex network connections in the insect’s brain that underlie behaviors ranging from feeding to mating.
Memories of Meals Influence Future Eating BehaviorNews
Brain cells involved in memory play an important role after a meal in reducing future eating behavior, a finding that could be key in understanding and fighting obesity, according to a study led by Georgia State University.
Microglia Transmit Pain to the Brain During StressArticle
Chronic pain is a multifaceted disorder that causes profound disability worldwide. It has long been known that psychological stress contributes to adverse chronic pain outcomes in patients, but it is unclear how this is initiated or amplified by stress. Now, researchers have published results showing that activation of microglia in the mouse spinal cord is responsible for increased pain sensitivity in response to stress.Read more
Case Study: Dr. Kaelberer Validates a Neuroepithelial Circuit using MiloArticle
How does the gut talk to the brain? In this new case study from ProteinSimple, we find out how Melanie Maya Kaelberer, a Postdoctoral Associate at Duke University, is using Single-Cell Western platform Milo to answer the question of how the gut can rapidly communicate with cranial nerves.Read more
A (Lab)Step Towards Reproducible ScienceArticle
The reproducibility crisis is holding back science. London-based Labstep, a start-up out of Oxford University, think that their tool can help make science more open and reproducible. That claim has now been given some concrete evidence with the announcement that the research contingent of the MRC Unit The Gambia at LSHTM will be trialling Labstep across their Banjul-based facility.Read more
Worried You are Dating a Psychopath? Signs to Look for, According to ScienceArticle
Here's what to look for.Read more