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How to Analyze Images with Invitrogen iBright Imaging Systems

Video

Capture images and analyze data from your western blots and gels efficiently and easily using the Invitrogen iBright Imaging Systems.

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Unlocking the Secrets of Brain Organization -in the Fruit Fly

Article

As many people spent the summer trying to keep the flies away from their fruit-bowls, an international group of scientists published one of the biggest and most important datasets in the field of connectomics to date, the complete 3D electron micrograph volume of the fruit-fly (Drosophila melanogaster) brain.

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Imaging the Brain at High Spatiotemporal Resolution

Webinar

Physics has long employed optical methods to probe and manipulate matter on scales from the infinitesimal to the immense. To understand the brain, we need to monitor physiological processes of single synapses as well as neural activity of a large number of networked neurons. Optical microscopy has emerged as an ideal tool in this quest, as it is capable of imaging neurons distributed over millimeter dimensions with sub-micron spatial resolution.

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Neuroscience at Super-Resolution [Image Gallery]

List

A gallery of beautiful images of brain cells at the sub-micron level.

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Now Anyone Can Tour the Fly Brain

Now Anyone Can Tour the Fly Brain

News

A new fly-through of the fly brain allows anyone to whizz past neurons and visit any of the 40 million synapses where neurons touch neuron. It’s a super-resolution view of the complex network connections in the insect’s brain that underlie behaviors ranging from feeding to mating.

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Defining the Dendritic Field of the Connections That Link Cerebral Hemispheres
News

Researchers at the Max Planck Florida Institute for Neuroscience have developed a new combination of technologies that allows them to identify the functional properties of individual synapses that link the two hemispheres and determine how they are arranged within a neuron’s dendritic field.

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Study Links Moving More in Older Age to Sharper Memory
News

Older adults who move more, either with daily exercise or even simple routine physical activity like housework, may preserve more of their memory and thinking skills, even if they have brain lesions or biomarkers linked to dementia, according to a new study. Nevertheless, more research must be done to prove a causative link between the two.

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Gene Therapy Promotes Nerve Regeneration
News

Researchers have shown that treatment using gene therapy leads to a faster recovery after nerve damage.

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Case Study: Dr. Kaelberer Validates a Neuroepithelial Circuit using Milo
Case Study: Dr. Kaelberer Validates a Neuroepithelial Circuit using Milo
Article

How does the gut talk to the brain? In this new case study from ProteinSimple, we find out how Melanie Maya Kaelberer, a Postdoctoral Associate at Duke University, is using Single-Cell Western platform Milo to answer the question of how the gut can rapidly communicate with cranial nerves.

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Microglia Transmit Pain to the Brain During Stress
Microglia Transmit Pain to the Brain During Stress
Article

Chronic pain is a multifaceted disorder that causes profound disability worldwide. It has long been known that psychological stress contributes to adverse chronic pain outcomes in patients, but it is unclear how this is initiated or amplified by stress. Now, researchers have published results showing that activation of microglia in the mouse spinal cord is responsible for increased pain sensitivity in response to stress.

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A (Lab)Step Towards Reproducible Science
A (Lab)Step Towards Reproducible Science
Article

The reproducibility crisis is holding back science. London-based Labstep, a start-up out of Oxford University, think that their tool can help make science more open and reproducible. That claim has now been given some concrete evidence with the announcement that the research contingent of the MRC Unit The Gambia at LSHTM will be trialling Labstep across their Banjul-based facility.

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Understanding the Role of BDNF on GABAergic neurotransmission
Understanding the Role of BDNF on GABAergic neurotransmission
Article

Researchers have identified a mechanism by which brain-derived neurotrophic factor (BDNF) can suppress GABAergic transmission in hippocampus. In this article, Dr. Rajamani Selvam explains how he and his team achieved these results, and their potential impact on the treatment of neurological disease.

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Light Sheet Imaging Helps Capture Zebrafish Neural Development
Light Sheet Imaging Helps Capture Zebrafish Neural Development
Article

A video showing the birth of an incredible network of neurons in the nervous system of a Zebrafish has won first prize at the Nikon Small World in Motion Awards, which highlight the best in photography and video captured through the microscope lens. We caught up with researchers behind the video to find out more.

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