A Yale-led team of researchers has identified specific gene combinations that can cause the deadly brain cancer glioblastoma, using new technology that can also pinpoint triggers of other types cancers.

Researchers have used CRISPR to correct the molecular mistakes that lead to microsatellite repeat expansion diseases, which include myotonic dystrophy types 1 and 2, the most common form of hereditary ALS, and Huntington's disease.

When a RNA molecule called Cdr1as was deleted from the genome of mice, the animals had problems filtering out unnecessary information – like patients suffering from neuropsychiatric disorders.