Experimental Alzheimer’s Drug Lecanemab Slows Cognitive Decline in Clinical Trial
A significant development in Alzheimer’s disease research has been announced by the drug company Eisai. In a press release, the company said that their investigational anti-amyloid beta (Aβ) protofibril antibody lecanemab has produced modest but highly statistically significant results in trial.
The Binomial Test
The Binomial test, sometimes referred to as the Binomial exact test, is a test used in sampling statistics to assess whether a proportion of a binary variable is equal to some hypothesized value. In this article, we explore the key features of this test and walk through an example test.
Our Urge To Eat Fatty Foods Is Caused by a Gut-Brain Signal
The temptation of a burger or pizza has surprisingly little to do with our taste buds, finds a new study. Instead, connections between our gut and brain dictate our obsession for fatty foods, say the authors.
A New Model Proposes an Autoimmune Model of Alzheimer's
Scientists have proposed a new mechanistic model for Alzheimer's disease, looking at it as a chronic autoimmune condition that attacks the brain rather than a brain disease.
Researchers Identify Ritalin's Effects on Dopamine in the Brain
Researchers have pinpointed how Ritalin – the drug used to treat ADHD – affects dopamine in the brain, explaining why Ritalin has varying effects on individuals.
CRISPR Screening: Studying Evolution in a Dish
CRISPR screening enables the rapid and unbiased identification of genes relevant to a specific biological pathway. In this article, we explore how researchers are using this cutting-edge tool to shape our understanding of biology and advance medicine.
Radically Rethinking Scientific Publication: The “Octopus” Model
Dr. Alexandra Freeman believes that the major problems associated with research culture in science can be traced back to one source: the current scientific publishing model. In this interview with Technology Networks, she explains why a novel approach, called Octopus, is a logical solution to these issues.
A Popular Theory About Depression Wasn’t "Debunked" by a New Review
A new paper that reviews the evidence around the serotonin “chemical imbalance” theory of depression has caused an online storm, with figures from across psychiatry commenting on the study’s merits and limitations. In this article, we take a look at what the paper has changed about our understanding of depression.
What Does the Endocannabinoid System Have To Do With Autism Spectrum Disorder?
To learn more about the link between endocannabinoids and ASD and how innovative models are helping to study the ECS and its effects on the developing brain, Technology Networks spoke to Drs. Karen Litwa and Ken Soderstrom from East Carolina University.
How To Build an Effective Protein Degrader
This guide highlights the four major stages of targeted protein degradation, the challenges at each step, and the questions you should ask yourself to ensure your final product will result in a complete protein degradation.
Fall in Love With Pipetting Again: Automated Liquid Handling
Download this guide to learn more about automated liquid handling solutions.
Spatial Transcriptomics: Understanding Gene Regulation in the Tissue Context
Download this listicle to explore spatial transcriptomics applications and key technologies including next-generation sequencing based-methods, In situ sequencing-based methods and In situ hybridization-based methods.
Recent Developments in Proteomics Research
Here, we take a closer look at some recent developments in the world of proteomics research.