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Unlocking the Secrets of Brain Organization -in the Fruit Fly

Article

As many people spent the summer trying to keep the flies away from their fruit-bowls, an international group of scientists published one of the biggest and most important datasets in the field of connectomics to date, the complete 3D electron micrograph volume of the fruit-fly (Drosophila melanogaster) brain.

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The Biomarkers Which Could be Used to Spot Alzheimer’s Earlier

Video

In this video, Sophie discusses the 'biomarkers' which could be used to spot Alzheimer's in its early stages.

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Customizing The Exome

Webinar

The introduction of exome analysis provides the opportunity to improve more findings compared to traditional genetic testing approaches and fixed panel-based genomic analyses. Large studies of many families using trio exomes and a genotype first approach have been incredibly powerful tools for gene discovery and identification of pathogenic variants in rare Mendelian disorders. Proband only exomes, however, require different methods of variant filtering which typically involve prioritisation of genes and/or variants based on phenotype.

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A Single Season of High School Football Causes Changes in the Teenage Brain

A Single Season of High School Football Causes Changes in the Teenage Brain

News

Researchers using a new type of magnetic resonance imaging to take brain scans of teenage football players suggest that just one season of playing might be enough to cause microscopic changes in the structure of the brain, even whilst wearing helmets and not sustaining concussions.

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Prozac Makes Crickets Calm
News

Why do animals differ in personality? Researchers at Linköping University used human drugs that alter two brain chemicals, serotonin and dopamine, to see if these drugs would change the behavior of animals.

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Dramatic Effects of Oil Spills on Senses
News

Exposure to crude oil significantly impaired olfactory function in the Atlantic stingray after just 48 hours of exposure which could detrimentally impact fitness, lead to premature death and cause knock on effects.

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The Cerebellum Makes Moves and Memories
News

The cerebellum, a structure found in the back of the skull, is known to be important for the control of movement, while the frontal cortex is responsible for cognitive functions such as short-term memory and decision making. However, as researchers continue to unlock the mystery of how billions of neurons in the brain interact, it is becoming more apparent that it is not that black and white.

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The Brain Bounces Back: Activity enables mice to overcome brain damage

The Brain Bounces Back: Activity enables mice to overcome brain damage

Article

Scientists removed an area of the somatosensory cortex in mice and found the animals could recover their behavioral deficit within two days.

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'Microdosers' of LSD and Magic Mushrooms are Wiser and More Creative
Article

Researchers just ran the first ever pre-registered scientific study on the microdosing of psychedelics and found some very promising results.

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Inflamyloid: What Is It and Why Is It Important in Alzheimer's Disease?
Article

Alzheimer’s disease (AD) is the leading cause of dementia worldwide. Classically, the “amyloid” hypothesis, which ties the disease’s spread to that of amyloid protein, is thought to underlie AD’s pathology. After years of mixed to negative results in clinical trials, new research is underway to investigate what role the brain’s own immune system plays in amyloid-driven disease; an “infl-amyloid” hypothesis.

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Through the Looking Glass of Single Cell Proteomics
Article

To pick apart the differences between individual cells in complex multicellular organisms, we need to look at cells one-by-one. This article takes a look at how several scientists in North America are using single cell proteomics (SCP) technologies to discern disease pathogenesis and enhance directed stem-cell differentiation.

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