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Latest Application Notes
A Continual Trials Approach to Spontaneous Object Recognition in Mice
Application Note

A Continual Trials Approach to Spontaneous Object Recognition in Mice

Tasks of spontaneous recognition are widely used to assess memory in rats and mice.
Visualization of Membrane Dynamics with Millisecond Temporal Resolution
Application Note

Visualization of Membrane Dynamics with Millisecond Temporal Resolution

Electrical stimulation of neurons combined with high-pressure freezing allows physiological activation of synaptic activity and precise control over the time frame of the inducted synaptic activity.
Quantitative live-cell analysis for optimization of culture conditions and evaluation of cell health in human induced pluripotent stem cell-derived neurons
Application Note

Quantitative live-cell analysis for optimization of culture conditions and evaluation of cell health in human induced pluripotent stem cell-derived neurons

In this application note, we describe methods and present validation data highlighting optimal culture conditions for evaluation of cell viability and neurite outgrowth in hiPSCderived neurons from Cellular Dynamic International.
HumSilencer Eliminates Electrical Hum Without Causing Signal Distortion
Application Note

HumSilencer Eliminates Electrical Hum Without Causing Signal Distortion

HumSilencer removes the most common source of background noise in electrophysiology experiments. This App note explains how.
Visualizing Subcellular Vesicles to Quantitate Autophagy in Neuronal Cells
Application Note

Visualizing Subcellular Vesicles to Quantitate Autophagy in Neuronal Cells

The role of autophagy is of particular interest in the study of neuronal cells, where it helps to maintain protein structure and function over long axonal distances.
Image-Based Analysis of a Human Neurosphere Stem Cell Model for the Evaluation of Potential Neurotoxicants
Application Note

Image-Based Analysis of a Human Neurosphere Stem Cell Model for the Evaluation of Potential Neurotoxicants

Here we demonstrate a 3D neurosphere model, composed of hNSCs, to conduct toxicity testing of several potential neurotoxicants.
Detection of RNA in the central and peripheral nervous system using the RNAscope® in situ hybridization assay
Application Note

Detection of RNA in the central and peripheral nervous system using the RNAscope® in situ hybridization assay

The RNAscope® in situ hybridization (ISH) assay provides a powerful method to detect gene expression within the spatial and morphological tissue context.
Neuronal Differentiation of hPSC-Derived Neural Progenitor Cells
Application Note

Neuronal Differentiation of hPSC-Derived Neural Progenitor Cells

Culture in BrainPhys™ Neuronal Medium results in cultures that are phenotypically mature and, after 65 days in culture, synaptically active.
A Monolayer Culture Method for Neural Induction of hPSCs
Application Note

A Monolayer Culture Method for Neural Induction of hPSCs

Method for neural induction using STEMdiff™ Neural Induction Medium in a monolayer culture system.
Multipette®/ Repeater® M4 Allows for Fast, Precise and Sterile Liquid Transfer in Cell Culture
Application Note

Multipette®/ Repeater® M4 Allows for Fast, Precise and Sterile Liquid Transfer in Cell Culture

This application note demonstrates the huge advantages offered by Multipette M4 in terms of accuracy and precision needed for many cell culture applications.
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