Latest Application Notes
A Continual Trials Approach to Spontaneous Object Recognition in Mice
Tasks of spontaneous recognition are widely used to assess memory in rats and mice.
Visualization of Membrane Dynamics with Millisecond Temporal Resolution
Electrical stimulation of neurons combined with high-pressure freezing allows physiological activation of synaptic activity and precise control over the time frame of the inducted synaptic activity.
Quantitative live-cell analysis for optimization of culture conditions and evaluation of cell health in human induced pluripotent stem cell-derived neurons
In this application note, we describe methods and present validation data highlighting optimal culture conditions for evaluation of cell viability and neurite outgrowth in hiPSCderived neurons from Cellular Dynamic International.
HumSilencer Eliminates Electrical Hum Without Causing Signal Distortion
HumSilencer removes the most common source of background noise in electrophysiology experiments. This App note explains how.
Visualizing Subcellular Vesicles to Quantitate Autophagy in Neuronal Cells
The role of autophagy is of particular interest in the study of neuronal cells, where it helps to maintain protein structure and function over long axonal distances.
Image-Based Analysis of a Human Neurosphere Stem Cell Model for the Evaluation of Potential Neurotoxicants
Here we demonstrate a 3D neurosphere model, composed of hNSCs, to conduct toxicity testing of several potential neurotoxicants.
Detection of RNA in the central and peripheral nervous system using the RNAscope® in situ hybridization assay
The RNAscope® in situ hybridization (ISH) assay provides a powerful method to detect gene expression within the spatial and morphological tissue context.
Neuronal Differentiation of hPSC-Derived Neural Progenitor Cells
Culture in BrainPhys™ Neuronal Medium results in cultures that are phenotypically mature and, after 65 days in culture, synaptically active.
A Monolayer Culture Method for Neural Induction of hPSCs
Method for neural induction using STEMdiff™ Neural Induction Medium in a monolayer culture system.
Multipette®/ Repeater® M4 Allows for Fast, Precise and Sterile Liquid Transfer in Cell Culture
This application note demonstrates the huge advantages offered by Multipette M4 in terms of accuracy and precision needed for many cell culture applications.