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Latest Application Notes

Application Note

Neuroinflammation Research Solutions With HTRF Assays

Download this application note to discover more about neuroinflammation and toxicity, including how HTRF assays can be applied to this area of research.
Application Note

TAU Protein Aggregation Assay Relevance to Alzheimer’s Disease and Tauopathies Research

In this app note, find out how HTRF technology can be used to improve our understanding of Tau-related neuronal disorders.
Application Note

Enhancing Micro-Flow Ionization in Mass Spectrometry

Download this tech note to learn how you can enhance your ionization, sensitivity, ion uptake efficiency and robustness when performing micro-LC/MS.
Application Note

Normalization in Western Blotting to Obtain Relative Quantitation

Download this free technical note to discover the principles of normalization using internal loading controls, and how to accurately normalize your western blot.
Application Note

Thermal Cycler Temperature Accuracy – A Comparison of Different Models

Download this application note to learn about thermal cycler temperature performance across different models, against manufacturers’ published specifications, and in isothermal, VeriFlex™, and gradient mode.
Application Note

A Continual Trials Approach to Spontaneous Object Recognition in Mice

Tasks of spontaneous recognition are widely used to assess memory in rats and mice.
Application Note

Visualization of Membrane Dynamics with Millisecond Temporal Resolution

Electrical stimulation of neurons combined with high-pressure freezing allows physiological activation of synaptic activity and precise control over the time frame of the inducted synaptic activity.
Application Note

Quantitative live-cell analysis for optimization of culture conditions and evaluation of cell health in human induced pluripotent stem cell-derived neurons

In this application note, we describe methods and present validation data highlighting optimal culture conditions for evaluation of cell viability and neurite outgrowth in hiPSCderived neurons from Cellular Dynamic International.
Application Note

HumSilencer Eliminates Electrical Hum Without Causing Signal Distortion

HumSilencer removes the most common source of background noise in electrophysiology experiments. This App note explains how.
Application Note

Visualizing Subcellular Vesicles to Quantitate Autophagy in Neuronal Cells

The role of autophagy is of particular interest in the study of neuronal cells, where it helps to maintain protein structure and function over long axonal distances.
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