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Latest Application Notes

Application Note

Image-Based Analysis of a Human Neurosphere Stem Cell Model for the Evaluation of Potential Neurotoxicants

Here we demonstrate a 3D neurosphere model, composed of hNSCs, to conduct toxicity testing of several potential neurotoxicants.
Application Note

Detection of RNA in the central and peripheral nervous system using the RNAscope® in situ hybridization assay

The RNAscope® in situ hybridization (ISH) assay provides a powerful method to detect gene expression within the spatial and morphological tissue context.
Application Note

Neuronal Differentiation of hPSC-Derived Neural Progenitor Cells

Culture in BrainPhys™ Neuronal Medium results in cultures that are phenotypically mature and, after 65 days in culture, synaptically active.
Application Note

A Monolayer Culture Method for Neural Induction of hPSCs

Method for neural induction using STEMdiff™ Neural Induction Medium in a monolayer culture system.
Application Note

Multipette®/ Repeater® M4 Allows for Fast, Precise and Sterile Liquid Transfer in Cell Culture

This application note demonstrates the huge advantages offered by Multipette M4 in terms of accuracy and precision needed for many cell culture applications.
Application Note

Cells in Double Emulsions for FACS Sorting

Capturing individual cells in 30 µm double emulsions,suitable for FACS sorting.
Application Note

Whole-Mount Slide Imaging in Traumatic Brain Injury Research

This application note describes how the TissueScope™ solution provides researchers with the opportunity to effectively map the entire brain, and link detailed cytoarchitectural maps with functional imaging data.
Application Note

Triggering with the Leica TCS SP5, TCS SP5 II and DM6000 CFS

This document provides detailed information about triggering with the Leica TCS SP5, TCS SP5 II and DM6000 CFS systems.
Application Note

Characterization of Pollen Samples with the Morphologi® G3SE

The Morphologi® G3 automated particle characterization system is an analytical tool that provides microscope quality images and delivers statistically significant data through the rapid analysis.
Application Note

3D Cell Culture: mimicking real tissue

Technological advances in the last couple of years have enabled 3D scaffolds to be engineered that offer a real proxy for the in vivo environment which can be easily and routinely used in a cell culture laboratory.

Alvetex Scaffold enables cells to develop natural, in vivo-like intercellular interactions, providing an ideal environment for real three-dimensional growth and nutrient exchange that is comparable to intra-capillary exchange in living tissues.

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