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Assessing the Functionality of PBMCs After Cryopreservation

Assessing the Functionality of PBMCs After Cryopreservation
Credit: iStock

Human peripheral blood mononuclear cells (PBMCs) are commonly used during the drug development process in T cell proliferation assays to determine whether a compound or drug will elicit a T cell response to a foreign substance.

As PBMCs continue to see an increase in use in the testing of new biological therapeutic compounds, ensuring purified cells retain functionality after cryopreservation is critical.

Download this app note to discover PBMCs that: 

  • Maintain function when isolated from fresh and cryopreserved leukopaks
  • Are reliable, reproducible and interchangeable
  • Can be used to generate experimental data with convenience

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