Mass Spec Solution for Short Gradient Analysis
Application Note Oct 01, 2019
High sample throughput in proteomics, like that in genomics, is highly desirable. Moreover, the highest analytical depth in proteomics is achieved on fractionated samples, requiring subsequent analysis of the individual fractions with short gradients to achieve reasonable overall measurement time per sample.
The timsTOF Pro with trapped ion mobility spectrometry (TIMS) offers additional separation power and increased peak capacity over instruments without trapped ion mobility separations. TIMS enables the powerful Parallel Accumulation Serial Fragmentation (PASEF) method for very high sequencing speed that is perfectly suited for proteome analysis on short gradients.