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Application Note

Sensitive Detection of HCPs Using PASEF

Rectangle Image
Application Note

Sensitive Detection of HCPs Using PASEF

In the rapidly expanding arena of biotherapeutic analysis and bioprocess development, the analysis of host cell proteins (HCP) at the ppm level is critical.

While ELISA is currently the gold standard for QC applications, the advantages of mass spectrometry are abundant, and it has the potential to eventually become the favored approach for this analysis.

Download this poster to learn how PASEF scans can:
• be applied to HCP analysis
• improve the sensitivity of routine peptide mapping
• provide high confidence in protein ID – even with only 1-2 peptides
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