Why Does Ketamine Fight Depression? Finding Answers at BNA 2019
A significant minority of major depressive disorder patients don’t respond to currently available antidepressant medication. A newly approved treatment, based on the "club drug" ketamine, could change that. In a session at the British Neuroscience Association’s Festival of Neuroscience 2019, the potential mechanisms of ketamine’s antidepressant action were put under examination.
Sensitivity vs Specificity
When developing diagnostic tests or evaluating results, it is important to understand how reliable those tests and therefore the results you are obtaining are. By using samples of known disease status, values such as sensitivity and specificity can be calculated that allow you to evaluate just that.
A Further Dimension to Drug Discovery: Combining 3D Culture With iPSCs
Running in parallel with advances in 3D cell culture is the growing use of human cells derived from induced pluripotent stem cells. Researchers are interested in testing drugs in the most physiologically relevant models possible, so it was only a matter of time before these two approaches converged – providing optimized systems for disease modeling and drug toxicity testing.
Of Currents and Photons: Should Neuroscientists Use Imaging or Electrophysiology to Monitor Neural Activity?
Once viewed as competing to be the best way of doing in vivo neuroscience, optical and electrical recording techniques are now being embraced as complementary methods in the quest to understand the brain.
Stimulation Gives Working Memory a Boost
A new study from Boston University researchers suggests that non-invasive stimulation using weak electrical current can reverse the effects of aging on working memory, at least temporarily, by synchronizing different rhythms of brainwave.
New Neurons Until Ninety: Discovering Neurogenesis in the Adult Hippocampus
Far from being a process that ends in maturity, a new study has found that the adult human brain is capable of producing new neurons until the tenth decade of life. This ability is substantially impaired in the brains of people with Alzheimer’s Disease (AD), which researchers say could help predict the onset of AD.
Can Physical Exercise Help Keep Our Brain Healthy?
Exercise might not be fun, but it’s good for your body. Over the years, science has well established that exercise can cut your risk of cardiovascular disease, type 2 diabetes, and some types of cancer. But the ways that exercise affects the brain are still under investigation, although new research suggests it may be essential for the growth of new neurons.
World Down Syndrome Day 2019: An Interview With Down Syndrome Expert Dr Julia Kinder
Dr Julia Kinder is a Down syndrome expert, national speaker, author, career consultant, fitness guru, and family practice physician. March 21st is World Down Syndrome Day, and we caught up with Julia to ask her how scientists, parents, and doctors can work together to benefit the lives of people with Down syndrome.
Lower Brain Connectivity Makes the Working Day Tougher for Night Owls
Working together with scientists at the University of Campinas in Brazil, and the University of Surrey, Birmingham researchers found that the brains of night owls have lower levels of connectivity in many brain regions which are implicated in the maintenance of consciousness.
Exploring the Genetics of Sleep
In this article, we explore the scientific research that looks at the links between our genes, why we sleep, and the negative impact a lack of sleep may have.