Pluripotent Stem Cells in Drug Discovery: Can We Stem the Tide of Unsuccessful Drugs?
Stem cells were first discovered in human cord blood in 1978. Why would we think they can be of more help now? This article delves into reasons behind the sudden interest in stem cells, and highlights how they can be used to advance drug discovery.
The Science of Why so Many People Believe in Psychic Powers
You would think that instances of proven psychic fraud over the years would weaken the credibility of psychic claims.
Addressing Controversy in ADHD: An Interview with Russell A. Barkley, PhD
We interviewed Russell A. Barkley, PhD, an internationally recognized expert on attention-deficit hyperactivity disorder (ADHD), to gain an insight into the disorder, its portrayal in the media and the future of ADHD research.
ROCKbusting Huntington’s and Probing Parkinson’s
At the Society for Neuroscience (SfN) conference last held in November 2018 in San Diego, a truly frightening number of posters were presented over nine sessions. In this article we look in-depth at posters shared by Charles River Laboratories, highlighting research into Huntington's Disease and Parkinson's Disease.
Case Study: Dr. Kaelberer Validates a Neuroepithelial Circuit using Milo
How does the gut talk to the brain? In this new case study from ProteinSimple, we find out how Melanie Maya Kaelberer, a Postdoctoral Associate at Duke University, is using Single-Cell Western platform Milo to answer the question of how the gut can rapidly communicate with cranial nerves.
Microglia Transmit Pain to the Brain During Stress
Chronic pain is a multifaceted disorder that causes profound disability worldwide. It has long been known that psychological stress contributes to adverse chronic pain outcomes in patients, but it is unclear how this is initiated or amplified by stress. Now, researchers have published results showing that activation of microglia in the mouse spinal cord is responsible for increased pain sensitivity in response to stress.
Addressing Real-world Challenges With Technology: An Interview With Christie Hunter Ph.D.
Christie Hunter is the Director of Applications at SCIEX where her and her team are tasked with developing new applications for SCIEX products, from screening for pesticides in our food supply through to molding the way cancer biomarkers are found. We spoke to Christie about her career, achievements and challenges for the future.
A (Lab)Step Towards Reproducible Science
The reproducibility crisis is holding back science. London-based Labstep, a start-up out of Oxford University, think that their tool can help make science more open and reproducible. That claim has now been given some concrete evidence with the announcement that the research contingent of the MRC Unit The Gambia at LSHTM will be trialling Labstep across their Banjul-based facility.
Worried You are Dating a Psychopath? Signs to Look for, According to Science
Here's what to look for.
Understanding the Role of BDNF on GABAergic neurotransmission
Researchers have identified a mechanism by which brain-derived neurotrophic factor (BDNF) can suppress GABAergic transmission in hippocampus. In this article, Dr. Rajamani Selvam explains how he and his team achieved these results, and their potential impact on the treatment of neurological disease.