Mass spectrometry (MS) plays a vital role in many aspects of our lives, from diagnosing illness and detecting food contaminants to fighting fraud. In order for a sample to be analyzed by MS, it must however, first be ionized. There are a number of ways of achieving sample ionization depending on the sample type, target analyte and desired workflow. In this article, we consider some common ionization techniques and sample types for which they are best suited.READ MORE
A key element to all mass spectrometry (MS) systems is the type of detector used to convert a current of mass separated ions into measurable signal. Different types of detectors are used depending upon factors including dynamic range, spatial information retention, noise and suitability to the mass analyzer. In this article, we consider some of the commonly used detectors.
Mass spectrometry (MS) is a key techniques in analytical chemistry and plays a role in many varied aspects of day-to-day life. In this article, we take a look at the fundamentals of MS, how it works, variations that can be used at each stage of the process and how they can be combined to suit different sample types or analytical questions.READ MORE
At the heart of any mass spectrometer is the mass analyzer. This component takes the ionized masses and separates them based on their mass-to-charge ratio (m/z). In this article, we consider some of the common types of mass analyzers, their advantages and disadvantages.READ MORE
Fred “Rusty” Gage is president of the Salk Institute for Biological Studies. After his recent plenary at the British Neuroscience Association’s Festival of Neuroscience, we spoke with Gage about his research into how our DNA repairs itself and how Alzheimer's disease causes neurons to undergo and identity crisis.READ MORE
At the British Neuroscience Association’s 2021 Festival of Neuroscience, a session was devoted to the discussion of new research working towards understanding ketamine’s mechanism of action and its potential use as a treatment for alcohol use disorder.READ MORE
The basis of our consciousness has perplexed experienced researchers, esteemed thinkers and the rest of humanity for several thousand years. At the British Neuroscience Association’s 2021 Festival of Neuroscience, University of Sussex Professor Anil Seth used his plenary lecture to dive deeper into new perspectives in our scientific approach to consciousness.
Liquid chromatography (LC) systems are the backbone of pharmaceutical and biopharmaceutical laboratories. However, with increasingly complex samples and efficiency pressures, scientists are seeking more confidence in their results. Can innovative two-dimensional LC (2D-LC) systems provide the answer?READ MORE