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What are the odds: Picking winners in the race to identify genetic components of gambling disorders
Gambling can have large negative consequences on the social, personal and financial lives of people. Disordered gambling (DB) is a term used to describe people with clinically diagnosed gambling addiction and those with gambling tendencies which trend towards—but don’t yet meet—the clinical threshold for diagnosis.
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The role of dopaminergic neurons in decision making
A crucial element for the survival of animals and humans is learning how to acquire rewarding stimuli—food, sex, and social rewards. While learning is powerful skill, nothing in the world remains the same for long, and learning must be adaptive in order to allow an animal to flexibly survive a changing environment.
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A new approach to treat asthma: Silencing nociceptor neurons in the lungs
Asthma sufferers regularly experience coughing, wheezing, chest tightness, and shortness of breath. It is a disease that targets the airways of the lung, and affects almost 1 in 10 people. The lung contains sensory neurons called nociceptors that alert us to pain or irritation.
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The memory game: Rapid formation of new associations
The formation of memories occurs rapidly, sometimes even after a single experience. Memory formation depends on an area of the brain known as the medial temporal lobe (MTL). However, the mechanism for how memories are so swiftly encoded is largely unknown and large technical challenges generally hinder experiments in awake behaving humans.
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Trippy research: Chemically-induced synesthesia
In April 1943, scientist Albert Hoffman ingested 250 micrograms of a substance he had synthesized five years prior. Less than an hour later, he “perceived an uninterrupted stream of fantastic pictures, extraordinary shapes with intense, kaleidoscopic play of colors.
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Stress resiliency and susceptibility: The neurocircuitry underlying the detrimental effects of chronic stress
Humans are remarkably resilient when confronted with tremendous amounts of stress and trauma. While most people are able to maintain balanced psychological and physical functioning, some people are vulnerable, or susceptible, to the negative biological, psychological, and social consequences of stress.
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Neural fundamentals: Sex differences in the nervous system
The brain is an intricate, plastic organ and scientists are only beginning to understand that differences between male and female brains are extremely complex and influenced by genetics, physiology, experience, and learning.
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Take a chance on me: How we integrate the choices of others into our decision-making
When making a decision, individuals have their own preferences and thresholds for what constitutes a ‘risky’ or ‘safe’ choice. These thresholds, however, can change when people are in social situations and know what choices others have made.
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An eye opening look at adult visual plasticity
Transplantation of embryonic neurons reopens visual plasticity in adulthood.
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Brain responses to speech predict early language outcomes in children with autism
An essential component of current research initiatives on brain disorders is to enhance our understanding of normal and atypical brain development and how certain trajectories impact or underlie disease-related phenotypes.
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