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Un-picking Pick’s Disease

Article   Aug 29, 2018 | by Adam Tozer, Ph.D

Scientist Explains How They Un-picked Pick’s Disease

Adam Tozer PhD

Science Writer



Case Study: Dr. Kaelberer Validates a Neuroepithelial Circuit using Milo


How does the gut talk to the brain? In this new case study from ProteinSimple, we find out how Melanie Maya Kaelberer, a Postdoctoral Associate at Duke University, is using Single-Cell Western platform Milo to answer the question of how the gut can rapidly communicate with cranial nerves.


Microglia Transmit Pain to the Brain During Stress


Chronic pain is a multifaceted disorder that causes profound disability worldwide. It has long been known that psychological stress contributes to adverse chronic pain outcomes in patients, but it is unclear how this is initiated or amplified by stress. Now, researchers have published results showing that activation of microglia in the mouse spinal cord is responsible for increased pain sensitivity in response to stress.


Quantifying Minimal Residual Disease in Chronic Myeloid Leukemia


Thanks to advances in therapeutics, chronic myeloid leukemia has been transformed from a deadly cancer into a manageable, chronic condition. However, patients have to stay on these drugs their whole lives, as there isn't a diagnostic test sensitive enough to detect traces of the disease that threaten a relapse. This article delves into the unmet need for such a test, and explains why droplet digital PCR (ddPCR) is a strong candidate that may fill this gap.



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