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POSTER

Applying Trapped Ion Mobility Separation (TIMS) in combination with ParallelAccumulation Serial Fragmentation (PASEF) for Analysis of Lipidomics Samples

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Untargeted lipidomics workflows target the profiling of changes in the lipidome in order to discover relevant lipids as potential biomarkers. This approach relies on robustly identifying a large number of lipids and statistically evaluating their relative abundances.

This poster presents an improved lipidomics identification workflow that is based a combination of LC-MS and TIMS separation together with a very fast data dependent MS/MS fragmentation (PASEF).

Download this poster to learn:

  • How a targeted approach allows TIMS separation of (close) isobaric lipids with resolution of 180
  • How alternative library search workflows increase identification confidence.
   

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