Latest How To Guides

Designing controls for some experiments involving cells can be tricky, especially for beginners who do not realize how many factors are at play and must be controlled during cell culture.

It is important to understand the advantages and disadvantages of different ways of detecting a protein of interest on a western blot membrane. Here, we consider the three main types of protein detection for western blot; radioactive, enzymatic, and fluorescent.

An important RNAi-based method to silence a gene is through the delivery of artificial RNA molecules called short hairpin RNAs (shRNAs). This guide will focus on the design, delivery and use of shRNAs to create a long-term knockdown of a targeted gene.

Immunohistochemistry (IHC) is a technique that capitalizes on the specificity of the immune system to examine tissue stained to demonstrate the presence of certain proteins. In this guide, we have provided a sample IHC protocol followed by tips and techniques to optimize your IHC staining.

This is the essential guide for any laboratory thinking of implementing a LIMS to improve processes and operational efficiency.

Download this free guide to storing your chemicals and reagents, including how to manage dangerous and delicate materials.

Publishing your work in well-respected academic journals is essential to progressing your career in your chosen field. The sheer volume of journals that are available can be daunting and the process in which they operate can be mystifying. To help you better understand how this process works and to give you a basic overview of what to expect, we’ve broken it down into 5 key steps.

PCR is a very popular and versatile tool for nucleic acid amplification. Download this guide for tips and tricks on troubleshooting your PCR problems.

The final stages of grad school are incredibly important for stabilizing your future goals. Download our free guide to get the best from your grad school leaving experience and get advice on writing your dissertation, finding a job and staying in touch.

This guide offers advice to those studying at grad school, including guidance on optimizing productivity, writing papers, communicating with staff and peers, and taking care of yourself!