5 Analytical Characterization Approaches for Biotherapeutics
List Jun 22, 2018 | by Victoria Ware
Biotherapeutics are highly complex molecules, needing detailed analysis to determine how they will behave in the human body.
Characterization of the biotherapeutic is needed at each stage of the drug development process and there are a variety of analytical characterization techniques available. This list highlights five approaches.
Download the list to learn more about the use of:
- Bio-layer interferometry to analyze biomolecular interactions
- HDX-MS to determine higher order structures
- Holographic video microscopy or dynamic light scattering to analyze aggregation
The efficacy and safety of a biopharmaceutical product depends on the product’s ability to maintain its molecular confirmation. As there is no single assay or parameter that sufficiently profiles the stability characteristics of a biological product, protocols for assessing stability can vary greatly. Download this list to get an overview of the general considerations that should be on your stability-assessment checklist.READ MORE