COVID-19 Can Cause Severe Inflammation in the Brain
A team of researchers has now shown that a severe inflammatory response can develop in the central nervous system of COVID-19 patients involving different immune cells around the vascular system and in the brain tissue.
Earworm Songs Help Boost Our Long Term Memory
New research from UC Davis suggests these experiences are more than a passing nuisance -- they play an important role in helping memories form, not only for the song, but also related life events like hanging out with friends, or watching other people hang with their friends on the '90s television show, Friends.
How Does the Brain Reboot After Deep Anesthesia?
Researchers are exploring how the brain reconstitutes consciousness and cognition after disruptions caused by sleep and anesthesia.
Caffeine Can’t Be Counted on To Fight Sleep Deprivation
Researchers have assessed how effective caffeine is in counteracting the negative effects of sleep deprivation on cognition.
Regulating Brain Circuit Signals To Tackle Obesity
Researchers have uncovered new aspects of satiation that relate to the little-known neural circuits and neurotransmitters involved in ending food consumption.
Resetting the Biological Clock With an On/Off Switch
The cells in our body follow the circadian clock, a 24-hour cycle. To study and potentially cure problems, scientists have created a compound that will elongate the cycle and that can be activated or deactivated using light.
Protective Role of Metabolic Enzyme in Glioblastoma Is Exposed
A new study published in Cancer Discovery uncovers a novel function for the metabolic enzyme medium-chain acyl-CoA dehydrogenase (MCAD) in glioblastoma. The findings suggest that by targeting MCAD, it is possible to cause irreversible damage and cell death to the cancer cells
How the Brain Strengthens Memories During Sleep
A new study shows that while we sleep, the brain produces particular activation patterns. When two of these patterns – slow oscillations and sleep spindles – gear into each other, previous experiences are reactivated. The stronger the reactivation, the clearer will be our recall of past events.
A Link Between Lithium Concentrations in the Brain and Depression
A research team has now proved that the distribution of lithium in the brains of depressive people is different from the distribution found in healthy humans.
Small Molecule Drug Could Be Used To Rejuvenate the Alzheimer’s Brain
Researchers have identified a small molecule that can be used to rejuvenate the brain and counteract memory loss in Alzheimer's disease.
Finding Drugs To Target Critical Enzymes Called Racemases
Scientists have explored racemases, enzymes linked to certain cancers that are critical to cell function, and have proposed new strategies for finding drugs that neutralize these enzymes.
A Novel Class of Radiosensitizers for Glioblastoma
Researchers have shown that the calcium channel blocker (CCB), mibefradil, inhibits DNA repair independent of its CCB activity. The findings could lead to a new class of mibefradil-based DNA repair inhibitors for glioblastoma.