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A new class of drugs under development to treat depression has shown some success by targeting brain cells' ability to respond to the chemical messenger glutamate. But the mechanism by which these experimental therapies work has remained unknown.

An experimental drug originally identified in a [US] National Cancer Institute library of chemical compounds as a potential therapy for brain and basal cell cancers improves the symptoms of mice with a form of the debilitating neurological disorder multiple sclerosis (MS), according to new research from NYU Langone Medical Center.

One of many light-sensitive pigments was found to set the retina’s own biological tempo while others set the body’s master clock.

All of us have our moods when we like to whistle an old melody or feel like tapping our feet to the latest hit. It turns out that cells in our brains can be equally moody, changing the tune of their electrical signals from time to time.

New software programs should help identify potential avenues for improved drug treatments for Alzheimer's.

Scientists at Duke Medicine are using transparent zebrafish to watch in real time as Cryptococcal meningitis takes over the brain. The resulting images are worthy of a sci-fi movie teaser, but could be valuable in disrupting the real, crippling brain infection that kills more than 600,000 people worldwide each year.

The role of the immune system in Alzheimer's disease is a hot topic, but exactly how the two are connected and what interventions could help lower risk remain a mystery. In a new study published in Nature Neuroscience, researchers in the Ann Romney Center for Neurologic Diseases at Brigham and Women's Hospital (BWH) investigate how genetic risk factors for Alzheimer's disease may influence a key type of immune cell.

Why is an object’s size perceived the same regardless of changes in distance?

More than half of older adults with clinical depression don't get better when treated with an antidepressant. But results from a multicenter clinical trial that included Washington University School of Medicine in St.

Most neuroscientific studies rely on a single experiment and assume their findings to be reliable. However, the validity of this assumption needs to be tested before accepting the findings as the ground truth.