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Epilepsy drug target implications for sleep disruption in brain disorders

A new study in a mutant fruit fly called sleepless (sss) confirmed that the enzyme GABA transaminase, which is the target of some epilepsy drugs, contributes to sleep loss. The findings, published online in Molecular Psychiatry, were led by Amita Sehgal, PhD, head of the Chronobiology Program at the University of Pennsylvania's Perelman School of Medicine.
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Scientists present a protein that facilitates the control of nerve cells by light

Networked nerve cells are the control center of organisms. In a nematode, 300 nerve cells are sufficient to initiate complex behavior. To understand the properties of the networks, researchers switch cells on and off with light and observe the resulting behavior of the organism.
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A better way to grow motor neurons from stem cells

Researchers report they can generate human motor neurons from stem cells much more quickly and efficiently than previous methods allowed. The finding, described in Nature Communications, will aid efforts to model human motor neuron development, and to understand and treat spinal cord injuries and motor neuron diseases such as amyotrophic lateral sclerosis (ALS).
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Survey shows spine surgeons need to screen more patients for anxiety and depression

Recommended presurgical psychological screening assessments largely ignored In a report published in the April edition of the Journal of Spinal Disorders and Techniques, a Johns Hopkins team says that only 10 percent of orthopaedic surgeons and neurosurgeons follow professional guidelines recommending routine psychological screenings of patients prior to major surgery for severe back and leg pain.
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Experimental cancer drug reverses schizophrenia in adolescent mice

Johns Hopkins researchers say that an experimental anticancer compound appears to have reversed behaviors associated with schizophrenia and restored some lost brain cell function in adolescent mice with a rodent version of the devastating mental illness.
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Endurance exercise improves neuronal connections to muscle fibers based on muscle-induced feedback

Endurance sport does not only change the condition and fitness of muscles but also simultaneously improves the neuronal connections to the muscle fibers based on a muscle-induced feedback. This link has been discovered by a research group at the Biozentrum of the University of Basel.
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Two new genes linked to intellectual disability discovered

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Computer maps 21 distinct emotional expressions, tripling the number of facial expressions that can be used for cognitive analysis

Researchers at The Ohio State University have found a way for computers to recognize 21 distinct facial expressions- even expressions for complex or seemingly contradictory emotions such as "happily disgusted" or "sadly angry.
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How we miss subtle visual changes, and why it keeps us sane

Ever notice how Harry Potter's T-shirt changes from a crewneck to a henley shirt in the "Order of the Phoenix," or how in "Pretty Woman," Julia Roberts' croissant inexplicably morphs into a pancake? Don't worry if you missed those continuity bloopers.
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Common hypotensive anaesthetic technique could increase risk of brain damage during surgery, researchers recommend adjustments

Researchers at the University of Adelaide have discovered that a commonly used anaesthetic technique to reduce the blood pressure of patients undergoing surgery could increase the risk of starving the brain of oxygen.
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