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New Genetic Mutation Linked to Intellectual Disability

Researchers report a new genetic mutation related to intellectual disability and discovered an excitatory synaptic activation signaling mechanism related to the mutation.

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Mental Fatigue May Involve a Potentially Toxic Chemical Buildup in the Brain

A workday doesn’t have to involve tiring manual labor to leave you feeling exhausted. A new study claims to have pinned down a functional reason why we feel fatigued after a day of mental effort.
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Web of Dreams: Spiders Appear To Enter an REM-Like Sleep State

A new study that peered at the translucent bodies of juvenile spiders has found evidence to suggest they may undergo a form of rapid eye movement (REM) sleep, a state closely associated with dreaming in mammals.


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How Important Is WIllpower in Resisting Temptation?

A study has found that people view willpower as exercising self-control, but do not think the same about avoiding temptation.
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Predicting Multiple Sclerosis Severity Simplified by Retina Exam

It is essential to assess the severity of multiple sclerosis (MS) in order to choose appropriate therapeutic measures, but this cannot be reliably done using existing methods. A study now shows for the first time that the retina can be used as a prognostic marker.
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Would You Still Smoke Cigarettes if They Made You Throw Up?

If you remember your first hit on a cigarette, you know how sickening nicotine can be. Researchers have now mapped out part of the brain network responsible for the negative consequences of nicotine, opening the door to interventions that could help people quit smoking.
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Enlarged Prostate Drug May Have Potential for Motor Neuron Disease

A drug currently used to treat an enlarged prostate could be repurposed to protect against the death of neurons in motor neuron disease.
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Neuronal Networks in a Dish Could Help Understand Schizophrenia

Researchers have used MoNNets, lab-grown renditions of brain-like cell assemblies, to study schizophrenia.
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How Cell "Antennae" Manage Dopamine Signals in the Brain

A new study has found that cilia on neurons in the brain have a key role in ensuring a specific dopamine receptor’s signals are properly received.
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Microbiome Molecule Can Induce Neuronal Inflammation

Research reports for the first time a pathway that begins in the gut and ends with a potent pro-inflammatory toxin in brain cells contributing to the development of Alzheimer’s disease (AD).
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