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33 Blood Metabolites Differ in Dementia
Scientists in Japan have identified metabolic compounds within the blood that are associated with dementia. The study revealed that the levels of 33 metabolites differed in patients with dementia, compared to elderly people with no existing health conditions.
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Cellular Blueprint of Multiple Sclerosis Lesions Created
Using brain tissue from humans, researchers at the National Institutes of Health’s National Institute of Neurological Disorders and Stroke built a detailed cellular map of chronic MS lesions, identifying genes that play a critical role in lesion repair and revealing potential new therapeutic targets for progressive MS.
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Gene Findings Advance Understanding of Rare Brain Disease Holoprosencephaly
If the cerebral hemispheres of the forebrain fail to divide properly in an unborn child, this results in holoprosencephaly. An MDC team led by Annette Hammes has discovered candidate genes that can positively influence the severity of this congenital malformation of the forebrain.
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Antibody Treatment Could Prevent Long-Term Effects of Brain Injury
In a new study, researchers identified a specific molecule in a part of the brain called the thalamus that plays a key role in secondary effects of brain injury, such as sleep disruption, epileptic activity, and inflammation. They also showed that an antibody treatment could prevent the development of these negative outcomes.
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A Single Brain Cell Can Control This Animal's Entire Foraging Strategy
Neuroscientists have developed a computer model to explain how a nematode worm searches for food, revealing that single brain cells can both sense the environment and control a whole animal’s foraging strategy.
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Office Air Quality May Impact Employee Performance
The air quality within an office can have significant impacts on employees’ cognitive function, including response times and ability to focus, and it may also affect their productivity, according to new research.
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Polygenic Risk Scores No Better Than Written Reports for Predicting Schizophrenia
Researchers went through the genetic and medical records of more than 8,000 schizophrenia patients. They found that a tool commonly used in research for evaluating a person’s genetic risk for a disease, called a polygenic risk score, was no better at predicting the outcome of a patient’s disease over time than written reports.
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Movie-Watching Mice Reveal Reliable Vision in the Brain
As mice watched movies, scientists watched their brains to see how vision could be represented reliably. The answer is that consistency in representation is governed by a circuit of inhibitory neurons.
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Sleep-Time Recovery Associated With Better Diet and Lower Alcohol Consumption
Good sleep-time recovery is associated with a health-promoting diet and health-promoting eating habits, as well as with lower consumption of alcohol, according to a new study investigating psychological and physiological well-being among working-age Finnish adults.
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Massages Stones Help Reveal How the Prefrontal Cortex Integrates Our Senses
An image of a beautiful beach conjures up certain sensations – one can imagine the warmth of the sun as it caresses the skin, and the sound of the water as waves break on the shore. But how is it that the human brain produces these impressions even when an individual isn’t actually standing on a beach, basking in the sun’s rays and listening to the sound of the waves?
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