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Hormone Helps To Prevent Muscle Loss in Mice Fed High Fat Diets
A new study suggests that a hormone known to prevent weight gain and normalize metabolism can also help maintain healthy muscles in mice. The findings present new possibilities for treating muscle-wasting conditions associated with age, obesity or cancer.
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How a Longevity Gene Protects Brain Stem Cells From Stress
A gene linked to unusually long lifespans in humans protects brain stem cells from the harmful effects of stress, according to a new study by Weill Cornell Medicine investigators.
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Sleep Proves Essential for Linking Emotion to Memories
Research suggests that groups of neurons activated during prior learning continue to form memories in the brain while a person sleeps.
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When Politicians Break Party Lines, Listeners' Brains Perk Up
New research has shown that politically incongruent statements are processed differently by the brain. Attention is increased, and the candidate’s conviction toward the stated position is also affects processing.
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Novel, Improved Vectors for Ocular Gene Therapy
Congenital retinal dystrophies are caused by defects in specific genes. Up until recently, there was no way to treat these conditions. However, the development of dedicated gene-delivery vehicles based on harmless viruses could be of clinical importance.
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Lab-Grown Brain Organoids Mature Like Infant Brains
A new study finds that three-dimensional human stem cell-derived organoids can mature in a manner that is strikingly similar to human brain development.
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Beta Blockers Show Ability To Repair Misshapen Brain Blood Vessels
Propranolol, a drug that is efficacious against infantile haemangiomas (resembling birthmarks), can also be used to treat cerebral cavernous malformations, a condition characterised by misshapen blood vessels in the brain and elsewhere, finds a new study.
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Stroke of Luck: Therapeutic Target Discovered in Blood–Brain Barrier
Researchers have now discovered that a stroke byproduct called acrolein activates the precursor of heparanase, an enzyme that degrades the glycocalyx in the blood–brain barrier. This knowledge could help to design new and effective therapeutics against post-stroke inflammation.
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Scientists Repair Injured Spinal Cord Using Patients’ Own Stem Cells
Intravenous injection of bone marrow derived stem cells (MSCs) in patients with spinal cord injuries led to significant improvement in motor functions, researchers from Yale University and Japan report in the Journal of Clinical Neurology and Neurosurgery.
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Brain Circuit Explains How We Change Behavior After a Mistake
Researchers have identified a neural pathway through which the brain detects errors and guides subsequent behavioral improvement. The research also suggests that neurostimulation of this brain pathway could provide an important mechanism for attention adjustments following behavioral errors.
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