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The proportion of people aged over 65 on antidepressants has more than doubled in two decades – according to new research led by the University of East Anglia.

The Golden Ratio, described by Leonardo da Vinci and Luca Pacioli as the Divine Proportion, is an infinite number often found in nature, art and mathematics. It’s a pattern in pinecones, seashells, galaxies and hurricanes. A new study adds human skulls to that list.

The secondary effects of traumatic brain injury (TBI), which can lead to long-term cognitive, psychological and motor system damage, that piqued the interest of a team of NJIT biomedical engineers. To counter them, they are developing a therapy, to be injected at the site of the injury, which shows early indications it can protect neurons and stimulate the regrowth of blood vessels in the damaged tissue.

Accumulation of amyloid protein plaques begins far before symptoms like memory loss in Alzheimer's disease. Identifying the origins of these plaques is therefore a key research goal. A new study could help those efforts by pinpointing the regions with the earliest emergence of amyloid in the brain of a mouse model of the disease, a finding backed up by subsequent study of amyloid in the human brain.

A study found that deep brain stimulation of an area in the brain called the subcallosal cingulate provides a robust antidepressant effect that is sustained over a long period of time in patients with treatment-resistant depression—the most severely depressed patients who have not responded to other treatments.

A new study has found that anticipating your own performance at work or school may hinder your ability to remember what happened before your presentation.

Researchers have discovered that Parkinson's Disease can be measured in the blood as an imbalance in the immune system.

Mu-opioid receptors (MOR) play a crucial role in how we experience pleasure and reward. A new paper reports how the MOR system contributes to the negative symptoms displayed in schizophrenia patients.

The method uses highly sensitive technology to detect the presence in the skin of “misfolded” alpha-synuclein (α-Syn) proteins that are the cause of nerve cell dysfunction and death in PD. It is much less invasive than current dependence on examining cerebrospinal fluid.

The findings have broad implications for our understanding of biological signaling processes and the design of over a third of the drugs on the market today.