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FDA Approves Ketamine-derived Nasal Spray for Depression
News   Mar 06, 2019

The U.S. Food and Drug Administration has approved Spravato (esketamine) nasal spray, in conjunction with an oral antidepressant, for the treatment of depression in adults who have tried other antidepressant medicines but have not benefited from them.

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Estrous Cycle Phase Influences Cocaine Craving in Rats
News   Mar 06, 2019

Menstrual cycle may influence addiction risk in women, according to a new study. In female rats, craving for cocaine during abstinence from the drug was stronger during estrus—the phase in which ovulation occurs—than non-estrus, and female rats were more prone to relapse of cocaine use than male rats.

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Improving Air Quality With an Electronic Nudge
News   Mar 06, 2019

Some parents who smoke at home can be nudged outdoors with a combination of coaching, lights and sound using technology that detects secondhand smoke in the house.

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The Brain Uses Sleep to Reduce DNA Damage
News   Mar 06, 2019

In a new study, published today researchers reveal a novel and unexpected function of sleep that they believe could explain how sleep and sleep disturbances affect brain performance, aging and various brain disorders.

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More Brain Connectivity Patterns Identified in Autism, Interpretation Unclear
News   Mar 06, 2019

Through the use of resting-state functional magnetic resonance imaging, reproducible brain connectivity patterns were identified in people with autism. However, as these phenotypes were only moderately linked to clinical symptoms, the usability of this imaging alone is limited as a diagnostic tool.

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Psychedelic Microdosing in Rats Shows Beneficial Effects
News   Mar 05, 2019

The growing popularity of microdosing – taking tiny amounts of psychedelic drugs to boost mood and mental acuity – is based on anecdotal reports of its benefits. Now, a study in rats by researchers at the University of California, Davis suggests microdosing can provide relief for symptoms of depression and anxiety, but also found potential negative effects.

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Genetic "Conductor" of Brain Stem Cells
News   Mar 05, 2019

A new study has shown how the Foxg1 gene, already involved in numerous processes of cerebral development and in rare disorders like Rett and West syndromes, plays a fundamental role in piloting the differentiation of stem cells, guaranteeing that neurons and glial cells are produced in the right quantity and at the right moment.

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TIGER Mouse Visualizes Vesicles
News   Mar 05, 2019

New research has devised a way to track tiny message-carriers in the brain that could prove useful in diagnosing and treating injuries, infections or diseases. The study uses a glowing mouse – appropriately dubbed the “TIGER mouse” – to trace the movement of information-rich particles found in bodily fluids throughout the body, called extracellular vesicles.

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Broken Heart? Look to the Brain
News   Mar 05, 2019

Scientists have shown for the first time that the brain is involved in the development of a heart condition called Takotsubo syndrome (TTS). They found that regions of the brain responsible for processing emotions and controlling the unconscious workings of the body, such as heart beat, breathing and digestion, do not communicate with each other as well in TTS patients as in healthy people.

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Assessing Sleep to Stratify Candidates for Parkinson's Trials
News   Mar 05, 2019

A large multi-centre study of more than 1,200 patients provides important predictors of Parkinson’s disease progression, which hopefully will allow better candidate selection for clinical trials and more effective therapy development.

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