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Blocking toxic-protein production in ALS
An approved drug that blocks an integrated stress response shows promise in preliminary tests against ALS and frontotemporal dementia.
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Helping Cells to Help Themselves in Models of Multiple Sclerosis
Diseases such as multiple sclerosis are characterized by damage to the ‘myelin sheath’, a protective covering wrapped around nerve cells akin to insulation around an electrical wire. Researchers have discovered how the body initiates repair mechanisms which will limit the extent of any damage to this sheath.
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Boy With Rare Brain Tumor One of First in UK to Receive Proton Beam Therapy Treatment
A 15-year old from West Sussex, diagnosed with a brain tumor last August, will become one of the first patients in the UK to receive state-of-the-art proton beam therapy treatment at a new £125 million center opened in Manchester.
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Can We Restore Memory Function in Alzheimer’s Disease?
Research reveals a new approach to Alzheimer's disease (AD) that may eventually make it possible to reverse memory loss, a hallmark of the disease in its late stages.
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New Tool Images Neural Activity With Near-Infrared Light
A new, groundbreaking tool for visualizing neural activity has implications for understanding brain functions and disorders, according to new research by University of Alberta scientists and a team of international collaborators.
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Eternal Sunshine of the Drug-less Mind
Forty to 60 percent of all people treated for substance use disorders relapse, presenting a major challenge to treatment success. New research shows that erasing memories that associate environmental cues with drug use significantly reduces drug seeking behaviors in rats, opening a potential avenue for developing more effective therapies to prevent relapse.
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Pre-symptomatic Skin Test for Prion Disease May Replace Brain Biopsy
Preclinical detection of prions has proven difficult, but new research suggests skin samples hold early signs of prion disease that precede neurologic symptoms.
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Sending Out the Wrong Signals
A signaling pathway to immune cells controlled by TGFβ could be involved in the progression of age-related macular degeneration
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New Role for Microvessels in Spinal Cord Injury
Previously unidentified roles have been established for endothelial cells: they engulf myelin debris following spinal cord injury, and contribute to the progression of inflammation, angiogenesis, and possibly, fibrotic scar formation.
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When Memory Loss Could Just Be Hearing Loss
A recent study published in the Canadian Journal on Aging, found that the majority of participants being evaluated for memory and thinking concerns and potential brain disorders had some form of mild to severe hearing loss, but only about 20 per cent of individuals used hearing aids. Among the participants, a quarter of them did not show any signs of memory loss due to a brain disorder.
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