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Oligodendrocytes, Microglia and Astrocytes Linked to 'Chemo Brain'
Three types of cells in the brain’s white matter show interwoven problems during the cognitive dysfunction that follows treatment with the cancer drug methotrexate, Stanford neuroscientists have found.
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Emerging Strategies for Treating Opioid-use Disorder
Anti-opioid immunopharmacotherapies (e.g., conjugate vaccines) that sequester drug peripherally, preventing opioids from reaching targeted receptors in the brain, have recently emerged as promising therapeutics.
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Shy People More At Risk of 'Hangxiety'
Very shy people are more likely to suffer “hangxiety” – anxiety during a hangover – than their extrovert friends, new research shows.
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Sunlight and Schizophrenia
Newborns with vitamin D deficiency have an increased risk of schizophrenia later in life, a team of Australian and Danish researchers has reported. The discovery could help prevent some cases of the disease by treating vitamin D deficiency during the earliest stages of life.
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Microglial Memories of Stress
Researchers have shown that microglia hold unique signatures of chronic stress that leave the animal more sensitive to future stressful experiences, evident by increased anxiety and immune responses. Eliminating microglia so that these "stress memories" could not be maintained did not prevent the increased anxiety in response to later stress but did prevent the hypersensitive immune response.
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Chronotherapies for Spinal Cord Injury?
In the hours and days following a spinal cord injury, the gears that control the body’s internal clocks fall profoundly out of sync, impacting body temperature, hormone fluctuation, immunity and the timing of a host of other bodily processes, according to new CU Boulder research.
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Genes Tied to Dementia Identified
A UCLA-led research team has identified genetic processes involved in the neurodegeneration that occurs in dementia — an important step on the path toward developing therapies that could slow or halt the course of the disease. The findings appear today in the journal Nature Medicine.
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Altered Progenitor Cell Signaling Linked to Autism
A recently completed study provides new information on functional changes in the brain connected with autistic spectrum disorders. The findings help identify factors related to the individual manifestation of autistic spectrum disorders and associated diseases.
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Adolescent Brain Cognitive Development Study Completes Enrollment of Nearly 12,000 9-10 Year Olds
The National Institutes of Health announced today that enrollment for the Adolescent Brain Cognitive Development (ABCD) Study is now complete and, in early 2019, scientists will have access to baseline data from all ABCD Study participants.
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Is Being a Night Owl Harmful to Health?
Night owls may have a higher risk of suffering from heart disease and type 2 diabetes than early risers. Researchers have uncovered a growing body of evidence indicating an increased risk of ill health in people with an evening preference as they have more erratic eating patterns and consume more unhealthy foods.
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