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Cryo-EM Reveals Potential Drug Target for Neurological Conditions
A team led by Van Andel Research Institute (VARI) scientists has revealed for the first time the atomic-level structure of TRPM2, a protein that may be a promising drug target for conditions such as Alzheimer's disease and bipolar disorder.
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What can we Tell from Your Smell?
Bodily odors of otherwise healthy animals sharing an environment with sick animals become like the odors of the sick animals.
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Protein “Trafficker” Implicated in Autism and Other Brain Disorders
Findings suggest that protein ASTN2 is a key regulator of dynamic trafficking of synaptic proteins and lend support to the idea that aberrant regulation of protein homeostasis in neurons is a contributing cause of complex neurodevelopmental disorders.
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Understanding What Makes Us Hot
A microdialysis study on mice aimed to determine mechanisms underlying the inflammatory response in the brain associated with fever that might be used to develop new strategies for treatment.
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Mitochondrial Peptide Protects Against Dementia
Research sheds new light on the protective role of a naturally occurring mitochondrial peptide, known as humanin.
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Gut Branches of the Vagus Nerve Are Essential Components of the Brain’s Reward and Motivation System
New study identifies novel pathway that could help inform new vagal stimulation approaches to affective disorders.
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Neurons Can Count
Researchers demonstrate that some brain cells fire mainly for quantities of three, others for quantities of four and others for other quantities.
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Party 'Pus: Ecstasy Makes Octopuses More Social
When people take MDMA, the drug popularly known as ecstasy, a rush of serotonin, dopamine, and oxytocin makes people more interested than they would normally be in connecting and sharing with other people. Now, researchers have made the surprising discovery that a species of octopus considered to be asocial responds to MDMA in the same way.
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Drug Addict-like Withdrawal From Quitting Junk Food
If you plan to try and quit junk food, expect to suffer similar withdrawal-type symptoms like addicts experience when they attempt to quit using drugs.
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Gambling Monkeys Illuminate Risk-Taking Brain Area
Monkeys who learned how to gamble have helped researchers pinpoint an area of the brain key to one's willingness to make risky decisions.
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