Adult cancer drugs showing promise against medulloblastoma now being used in pediatric clinical trial
The quest to improve survival of children with a high-risk brain tumor has led St. Jude Children’s Research Hospital investigators to two drugs already used to treat adults with breast, pancreatic, lung and other cancers.
Neurobiologists find chronic stress in early life causes anxiety, aggression in adulthood
In recent years, behavioral neuroscientists have debated the meaning and significance of a plethora of independently conducted experiments seeking to establish the impact of chronic, early-life stress upon behavior – both at the time that stress is experienced, and upon the same individuals later in life, during adulthood.
Antidepressants during pregnancy linked to preterm birth
Antidepressant medications taken by pregnant women are associated with increased rates of preterm birth. This finding reinforces the notion that antidepressants should not be used by pregnant women in the absence of a clear need that cannot be met through alternative approaches, say researchers from Brigham and Women's Hospital, Vanderbilt University, MetroWest Medical Center and Tufts Medical Center.
Immunotherapy approach to Alzheimer's studied in fly models
Developing treatments that slow, if not halt, the neuronal loss and cognitive decline of Alzheimer's disease (AD) has proven to be a challenge. Among the scientists who have taken on that challenge are researchers at the University of Florida's McKnight Brain Institute in Gainesville, using the fruit fly Drosophila melanogaster as a model.
New clue to autism found inside brain cells
The problems people with autism have with memory formation, higher-level thinking and social interactions may be partially attributable to the activity of receptors inside brain cells, researchers at Washington University School of Medicine in St.
Landmark study to guide protocol for stroke patients
Neurologists have long debated how to help prevent certain stroke patients from suffering a second stroke. Now research from the University of North Carolina (UNC) School of Medicine provides the first evidence for which course of treatment is truly best for patients with poor collateral blood vessel formation near the site of stroke: they should have their blood pressure lowered to normal levels.
Toadfish study finds protons act directly as nonquantal neurotransmitters in concert with classical neurotransmission mechanisms
While probing how organisms sense gravity and acceleration, scientists at the Marine Biological Laboratory (MBL) and the University of Utah uncovered evidence that acid (proton concentration) plays a key role in communication between neurons.
Nasal spray delivers new type of depression treatment
A nasal spray that delivers a peptide to treat depression holds promise as a potential alternative therapeutic approach, research from the Centre for Addiction and Mental Health (CAMH) shows.
The unconscious mind can detect a liar—even when the conscious mind fails
When it comes to detecting deceit, your automatic associations may be more accurate than conscious thought in pegging truth-tellers and liars, according to research published in Psychological Science, a journal of the Association for Psychological Science.
Researchers use DNA therapy in lab mice to improve cochlear implant functionality
One in a thousand children in the United States is deaf, and one in three adults will experience significant hearing loss after the age of 65. Whether the result of genetic or environmental factors, hearing loss costs billions of dollars in healthcare expenses every year, making the search for a cure critical.