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Circular RNA Linked to Brain Function

When a RNA molecule called Cdr1as was deleted from the genome of mice, the animals had problems filtering out unnecessary information – like patients suffering from neuropsychiatric disorders.
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Complete Connectome of a Learning and Memory Center Mapped

The complete connectome of the Drosophila melanogaster larvae mushroom body has been mapped.
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Brain-in-a-Dish Models Neuroinflammation

A human stem cell-based model of a rare, but devastating, inherited neurological autoimmune condition called Aicardi-Goutieres Syndrome has been created.
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siRNA Treatment for Brain Cancer Stops Tumor Growth in Mouse Model

Early phase Northwestern Medicine research published in PNAS has demonstrated a potential new therapeutic strategy for treating deadly glioblastoma brain tumors.
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Genetic Basis of Radiation-induced Brain Cancer Identified

Neuroscientists have uncovered the genetic basis for why many long-term survivors of childhood cancer develop meningiomas, the most common adult brain tumour, decades after their treatment with cranial radiation.
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Pathological Hallmarks of Alzheimer's Disease in Old Chimpanzee Brains

Kent State researchers provide evidence of Alzheimer's Disease pathology in aged Ape brains.
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Human Gut Microbe May Herald New Treatment for Multiple Sclerosis

Of three bacterial strains, researchers discovered that one microbe, Prevotella histicola, effectively suppressed immune disease in the preclinical model of MS.
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Necroptosis Pathway Implicated in Alzheimer's Disease

Researchers find first evidence that activation of the necroptosis pathway is closely linked with Alzheimer’s Disease severity.
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Diabetes Drug Could Help Treat Parkinson's Disease

A drug commonly used to treat diabetes may have disease-modifying potential to treat Parkinson’s disease, a new UCL-led study suggests, paving the way for further research to define its efficacy and safety.
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A Blood-based Screening Test for Alzheimer's

Research suggests that measures of amyloid beta in the blood have the potential to help identify people with altered levels of amyloid in their brains or cerebrospinal fluid.
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