BioFocus DPI Enhances ADME/PK Laboratory Bioanalytical Capabilities
News Feb 27, 2009
BioFocus DPI has announced that it has strengthened its ADME/PK Laboratory bioanalytical capabilities through the installation of a Waters® Xevo™ TQ Mass Spectrometer. As one of the first European-based CROs to use this instrument, ADME/PK Laboratory enhances its ability to identify drug metabolites for customers.
The use of the Xevo™ TQ-MS combined with Waters UltraPerformance LC® (UPLC) technology increases BioFocus DPI ADME/PK Laboratory’s throughput and allows accurate measurements to both quantify and confirm the identity of metabolites in a wide range of biological fluids and tissues.
For molecules that would have a poor response using standard technologies, the Xevo™ TQ-MS will increase the likelihood of detection. In addition to bioanalysis, ADME/PK Laboratory offers high-quality services backed by expert consultancy - extending from discovery ADME to in vivo pharmacokinetics.
“We are building ADME/PK Laboratory’s advanced bioanalysis service to provide the best ADME data to support drug discovery programs for our UK, US and European clients,” said Chris Newton, SVP BioFocus DPI. “With this newly installed instrument providing greater sensitivity, accuracy and speed, we further enhance the service that we deliver - whether this is for a small scale study or as part of an integrated drug discovery program.”
Exposure to Low Levels of BPA during Pregnancy Can Lead to Altered Brain DevelopmentNews
New research in mice provides an explanation for how exposure to the widely used chemical bisphenol A (BPA) during pregnancy, even at levels lower than the regulated “safe” human exposure level, can lead to altered brain development and behavior later in life.READ MORE
Moving Toward a Future Free of Drug-Induced Hearing LossNews
A new special publication orchestrated by five of the nation's leading hearing experts compiles the latest research into hearing loss caused by drugs and solvents - how it occurs, how to treat it, and how to prevent it.READ MORE
3-D Tissue Model of Developing Heart Could Aid Drug Safety Testing for Pregnant WomenNews
Parents and doctors often have to consider the mother's health as well as the potential risk regarding how medication could affect their baby. Researchers have developed a process to make a 3D tissue model that could mimic early stage human heart development, which could aid drug safety testing and help determine a drug's effects on fetal development.READ MORE
Comments | 0 ADD COMMENT
World Congress on Advanced Pharmacy and Clinical Research
Jul 16 - Jul 17, 2018
11th International Conference and Exhibition on Metabolomics & Systems Biology
May 17 - May 19, 2018
6th Annual Congress on Biology and Medicine of Molecules
Sep 17 - Sep 18, 2018