Epistem Announces Collaboration with GSK
News Mar 14, 2012
Epistem plc, has announced a three year biomarker collaboration with GlaxoSmithKline in the field of fibrosis research.
The collaboration will focus on identifying key characteristics of diseased fibrotic tissue on which Epistem will apply its proprietary RNA-Amp™ technology to facilitate building an in depth understanding of the disease.
RNA-Amp™ is highly sensitive amplification technology which is able to provide gene expression information from small tissue samples and low of numbers of cells e.g. those obtained from the bulb of cells at the base of a single hair follicle, as well as laser captured micro dissected (LCM) samples.
Epistem is now the preferred partner of choice for a range of pharmaceutical companies providing gene expression biomarker information to support drug development programmes.
In addition to its amplification technology, Epistem brings its well respected cell and molecular biology expertise to the collaboration.
Epistem’s broad platform allows protein and gene expression biomarkers to be identified in important disease pathways at an early stage of pre-clinical validation for translation through to later stage clinical validation and patient stratification.
Animal venoms are the subject of study at research center based at the Butantan Institute in São Paulo. But in this case, the idea is not to find antidotes, but rather to use the properties of the venoms themselves to identify molecular targets of diseases and, armed with that knowledge, develop new compounds that can be used as medicines.