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Laboratories at Children’s Hospital Boston to Use Protein Forest’s Digital ProteomeChip™ System

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Protein Forest™ has announced that Children’s Hospital Boston has recently installed the digital ProteomeChip™ System (dPC™) to use in a recently NIH funded study entitled “Multi-disciplinary Approach to the Study of Chronic Pelvic Pain (MAPP) Research Network (U01) Discovery Site”.

This study will be carried out in the laboratories of Keith Solomon, PhD., Assistant Professor of Orthopedic Surgery at Harvard Medical School and Administrative Director of the Proteomics Center at Children’s Hospital Boston, Richard Lee, MD, Assistant Professor of Surgery (HMS), Marsha Moses, Professor of Surgery (HMS), and Director of the Vascular Biology Program (CHB), and the Proteomics Center at Children’s Hospital Boston, under the direction of Hanno Steen, Ph.D., Assistant Professor of Pathology and Systems Biology (HMS).

Dr. Solomon’s lab had been evaluating technologies to discover new biomarkers in urine and has selected the dPC system for this study. The ability to identify new potential biomarkers never before seen with other methods, the analysis and the ease of use were critical factors in selecting the dPC platform for this study.

The ProteomeChip system fractionates and concentrates proteins or peptides by parallel isoelectric focusing in 30 minutes for superior mass spec analysis. Additionally, pI information from the dPC prefractionation enables rapid discovery of post-translational modification based biomarkers.