Laureate and Iconic Announce Immunoprotein Manufacturing Agreement
News May 11, 2006
Laureate Pharma, Inc. has announced that it has entered into a biopharmaceutical manufacturing agreement with Iconic Therapeutics, Inc. for cGMP manufacture of hI-con1, a "bi-functional immunoprotein."
"Iconic Therapeutics has a unique bi-functional immunoprotein for the treatment of wet adult macular degeneration and cancer and we are very pleased to be working with them on this exciting product," said Robert J. Broeze, Ph.D., President and Chief Executive Officer of Laureate Pharma.
"We look forward to a productive and successful relationship with Iconic Therapeutics."
"Our partnership with Laureate Pharma is an important aspect of our manufacturing strategy and our plans to initiate clinical evaluation of hI- con1 protein," said Michael I. Sherman, Ph.D., President of Iconic Therapeutics.
hI-con1™ protein is a "bi-functional immunoprotein," so called because it contains two functional domains connected by a "hinge," and each portion has a specific role to play in the protein's activity.
One domain of the hI- con1™ is a "homing sequence" that targets pathological cells whereas the other portion, the "effector sequence," is the part of an antibody that signals the immune system to destroy the targeted cells.
In addition to potential therapeutic utility in wet adult macular degeneration and many solid cancers, hI-con1™ has the prospect of being useful in treating other diseases as well.