LipidXplorer: A Software for Consensual Cross-Platform Lipidomics
News Mar 01, 2012
LipidXplorer processes spectra acquired on any type of tandem mass spectrometers; it identifies and quantifies molecular species of any ionizable lipid class by considering any known or assumed molecular fragmentation pathway independently of any resource of reference mass spectra. It also supports any shotgun profiling routine, from high throughput top-down screening for molecular diagnostic and biomarker discovery to the targeted absolute quantification of low abundant lipid species. Full documentation on installation and operation of LipidXplorer, including tutorial, collection of spectra interpretation scripts, FAQ and user forum are available through the wiki site.
The full article is published online in PLoS ONE and is free to access.
Retrained Enzyme is Biocatalysis MilestoneNews
TU Graz researchers managed for the first time ever to ‘retrain’ an enzyme to build ring-shaped molecular structures instead of performing its natural task of reducing double bonds. The work was published in Angewandte Chemie, and is relevant for the production of pharmaceuticals and plant protection products.
Laser Pulses and Fluorescence Enable Metabolite ViewingNews
In the search for new sources of drugs, biodegradables and biofuels scientists have come to realize that life itself could be the solution, using natural metabolites produced by bacteria to produce vital compounds like penicillin. Identifying which cells are most useful for this goal has proved a huge challenge, but a new system using fluorescence and lasers has enabled metabolite viewing in real time in algae cells.READ MORE
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