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Resurrecting Ancient Proteins Reveals Origin of Protein Regulation

News   Mar 09, 2020 | Original story from the Howard Hughes Medical Institute

 
Resurrecting Ancient Proteins Reveals Origin of Protein Regulation

In this simulation of two ancient proteins, Aurora A (gray) shifts into a new structure when activated by TPX2 (blue). TPX2 relies on the allosteric networks of Aurora A (pink spheres) to twist it into its new shape. Credit: Dorothee Kern/Brandeis University/HHMI

 
 
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