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Roche and the Medicines Patent Pool Sign Agreement for Treatment of CMV in HIV Patients
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CMV is a viral infection that can result in loss of vision and greater risk of death in people living with HIV. This infection affects around 1 in 10 people living with HIV in low-and middle-income countries.
The supply agreement between the Medicines Patent Pool and Roche will substantially improve access to an easy-to-take oral medicine to treat CMV, Valcyte – by making it up to 90% cheaper in 138 developing and emerging countries than it is currently available. The Medicines Patent Pool and Roche will consider adding more countries to the initial scope if there is a need and will also explore licensing and technology transfer as a second step to help local production of Valcyte and increase access to Valcyte in developing countries.
“The agreement announced today will make an oral treatment for CMV available at lower prices, to help break a cycle of lack of screening and treatment in many countries. With medicines available, HIV treatment providers can work on wider diagnosis and treatment and prevent avoidable blindness in people living with HIV,” said Greg Perry, Executive Director of the Medicines Patent Pool.
“This agreement demonstrates how working together can improve the availability of treatments for people in resource-limited countries. Roche is committed to making Valcyte available to patients suffering from HIV-related CMV infections in developing countries. Our aim is to provide access to affordable Valcyte that is produced under quality conditions and increase the number of people who access and benefit from our products,” said Daniel O’Day, COO of Roche Pharma.
Treatment of CMV is typically difficult to administer, requiring several injections to the eye. This requires hospitalisation of patients and care by highly trained staff , which are often not sufficiently available in developing countries. The oral treatment Valcyte is an alternative, but due to a number of reasons, including lack of screening and high prices, patients in developing countries have not been able to receive it.
This lower price should also help create a new market for Valcyte, stimulating greater treatment of CMV. With Roche now supplying lower-cost Valcyte, governments, treatment providers and funders can ramp up efforts to ensure screening for CMV becomes part of routine HIV care and people can access treatments to preserve their sight and extend their lives.
