Thermo, SRI International Collaborate to Enhance Small Molecule Research
News Jul 11, 2017
Thermo Fisher Scientific, recently announced the results of a collaboration agreement to enable researchers to combine the results of high-resolution Orbitrap LC/MS experiments with highly curated and organism-specific metabolic pathway and genome data for quick and effective mass spectrometry-based small molecule research and analysis.
The outcome of a successful collaboration, researchers now have a direct link between the Thermo Scientific Compound Discoverer 2.1 software platform for small molecule research and SRI International’s BioCyc, a collection of 9,300 databases that provide electronic reference sources on the metabolic pathways and genomes of many organisms. The ability to automatically and interactively overlay statistical data onto these pathways can facilitate the biological interpretation of results obtained from a metabolomics experiment. Ultimately, this new link is expected to speed data analysis for Compound Discoverer users and enable them to visualize many individual compound measurements to gain a comprehensive understanding of biological processes in an experiment.
Today, metabolomics researchers can measure thousands of small molecules, but it can be challenging to know which cellular systems are behaving differently in the studied condition compared to a control,” said Andreas Huhmer, director, proteomics and metabolomics marketing, chromatography and mass spectrometry, Thermo Fisher. “The new integration will allow scientists using Compound Discoverer to automatically map the most detected compounds to BioCyc metabolic pathway diagrams, and to connect additional experimental data, such as relative abundance or differential expression, onto the pathways.”
“We are delighted to bring the power of BioCyc to Thermo Fisher’s customers through a system that’s intuitive and easy to use,” said Peter Karp, director, bioinformatics research group, SRI International. “Scientists can now follow a link from Compound Discoverer to a BioCyc metabolic pathway page to gain access to a comprehensive knowledge-hub of genome and pathway information.”
Thermo Fisher and SRI International presented information resulting from the collaboration at the 13th Annual Conference of the Metabolomics Society, June 25-29 in Brisbane, Australia.
This article has been republished from materials provided by Thermo Fisher Scientific. Note: material may have been edited for length and content. For further information, please contact the cited source.
CRISPR Reveals New Targets for Promising Cancer DrugsNews
Novel screening method identifies new drug targets that could potentially enhance the effectiveness of PD-1 checkpoint inhibitors, a promising new class of cancer immunotherapy.READ MORE
Sysmex Partners with Laboratories to Deliver Improved QC ManagementNews
Sysmex America has announced its latest innovation: a way to make quality assurance easier and more risk free than manual quality control processes.READ MORE
Comments | 0 ADD COMMENT
Like what you just read? You can find similar content on the communities below.Analysis & Separations Applied Sciences Genomics Research Informatics & Automation Proteomics & Metabolomics
To personalize the content you see on Technology Networks homepage, Log In or Subscribe for FreeLOGIN SUBSCRIBE FOR FREE
EMBL Course: Next Generation Sequencing: RNA Sequencing Library Preparation
Apr 23 - Apr 27, 2018
EMBO Practical Course: Microbial Metagenomics: A 360º Approach
Apr 23 - Apr 30, 2018
EMBL Course: Next Generation Sequencing: Whole Genome Sequencing Library Preparation
Apr 16 - Apr 20, 2018
EMBO Workshop: Integrating Systems Biology: From Networks to Mechanisms to Models
Apr 15 - Apr 17, 2018