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Latest Posters
Effects of cannabinoids on cholinergic-mediated contraction of human bronchi
Poster

Effects of cannabinoids on cholinergic-mediated contraction of human bronchi

The current study was performed to investigate the role of cannabinoid (CB) receptors on the cholinergic contraction of isolated human airways. Results obtained with WIN55,212-2 (CB1/CB2 agonist), JWH-133 (CB2 agonist) and CB receptor selective antagonists suggest that CB1-receptor stimulation inhibits the cholinergic contraction in human isolated bronchi through stimulation of prejunctional receptors, located to post-ganglionic cholinergic nerves.
DISTRIBUTION OF SAa2,6GAL AND SAa2,3GAL LINKED SURFACE RECEPTORS IN HUMAN RESPIRATORY TRACT AND ASSOCIATION WITH INFLUENZA VIRUS REPLICATION
Poster

DISTRIBUTION OF SAa2,6GAL AND SAa2,3GAL LINKED SURFACE RECEPTORS IN HUMAN RESPIRATORY TRACT AND ASSOCIATION WITH INFLUENZA VIRUS REPLICATION

To investigate the level of SAa2,6Gal and a2,3Gal linked receptors on human bronchial epithelial cells, and relate this to the ability of both human and avian influenza viruses to infect bronchial epithelial cells
Inflammatory Markers in Leg Ulcer Fluid from Chronic Venous Insufficiency
Poster

Inflammatory Markers in Leg Ulcer Fluid from Chronic Venous Insufficiency

The purpose of our study was to evaluate soluble matrixmetalloproteinases (MMPs) and their inhibitor (TIMP1) associated to leg ulcer wound fluid in comparison with the tissue localized ones. We aimed to develop an easy-to-perform protocol for the quantification of soluble MMPs / TIMP and associate the obtained levels with the disease stage and prognostic.
Biomarker Discovery Strategy for Trisomy 21 Using iTRAQ and 4800 Plus MALDI TOF/TOF
Poster

Biomarker Discovery Strategy for Trisomy 21 Using iTRAQ and 4800 Plus MALDI TOF/TOF

Plasma proteins serve as good indicators of disease as there are representative proteins from several cellular processes and thus a potential source for biomarker discovery. The large dynamic range of plasma proteins makes the analysis very challenging, as a large number of low abundance proteins are masked by a few high abundance proteins.
Antibody Array-Based Analysis of Expression Levels in Protein Mixtures Extracted from Formalin-Fixed Paraffin-Embedded (FFPE) Material using ULS Labeling
Poster

Antibody Array-Based Analysis of Expression Levels in Protein Mixtures Extracted from Formalin-Fixed Paraffin-Embedded (FFPE) Material using ULS Labeling

Protein was extracted from 7-year old FFPE samples of B-cell lymphoma and mamma carcinoma, followed by ULS labeling. Samples were used for single or two color assays using a custom-made antibody array. We observed differential expression levels for several captured analytes. In B-cell lymphoma, expected high levels of IgM were detected, while high levels of CA19-9, a putative marker, were found for the breast cancer tissue.
Antibody Array-Based Analysis of Expression Levels in Protein Mixtures Extracted from Formalin-fFxed Paraffin-Embedded (FFPE) Material using ULS Labeling
Poster

Antibody Array-Based Analysis of Expression Levels in Protein Mixtures Extracted from Formalin-fFxed Paraffin-Embedded (FFPE) Material using ULS Labeling

Protein was extracted from 7-year old FFPE samples of B-cell lymphoma and mamma carcinoma, followed by ULS labeling. Samples were used for single or two color assays using a custom-made antibody array. We observed differential expression levels for several captured analytes. In B-cell lymphoma, expected high levels of IgM were detected, while high levels of CA19-9, a putative marker, were found for the breast cancer tissue.
The Impact of the PCK1 Gene and PPCK1 Promoter Polymorphism 232C→G on the Incidence of TIIDM in Oji-Cree Natives of Ontario
Poster

The Impact of the PCK1 Gene and PPCK1 Promoter Polymorphism 232C→G on the Incidence of TIIDM in Oji-Cree Natives of Ontario

The reported incidence of Type II Diabetes Mellitus (TIIDM) in Oji-Cree Natives is the highest in the world. This poster presents the impact of the PCK1 gene on TIIDM incidence in Oji-Cree Natives with particular attention to the role of SNP 232C→G on the transcription rate of phosphoenolpyruvate carboxykinease (PPCK1).
Combined Immune Parameters and X-ray data in Early Prediction of Anti-Tuberculosis Chemotherapy Response
Poster

Combined Immune Parameters and X-ray data in Early Prediction of Anti-Tuberculosis Chemotherapy Response

20 tuberculosis (12 slow-responders and 8 fast responders) patients were treated with directly observed short course anti-tuberculosis chemotherapy. Chest X-ray was performed. sICAM-1 and suPAR were measured in serum by ELISA, TNFRs using the luminex technology. General discrimination analysis on selected analytes gave, 91.66% and 87,50% correctly classify fast responders and slow responder respectively. The support vector machine analysis gave 100% correct classification.
Rapid Solution Exchange and Ligand-Gated Channel Studies on the PatchXpress 7000A Automated Patch Clamp System
Poster

Rapid Solution Exchange and Ligand-Gated Channel Studies on the PatchXpress 7000A Automated Patch Clamp System

The PatchXpress® 7000A patch clamp system is an automated electrophysiology workstation that allows users to increase throughput of research quality recordings and to measure ion channel activity from nearly any channel type.
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