A Computational Model of Mood and Future Prospects
Poster May 04, 2018
Rachel Bedder, Bastien Blain, Emily Lowther, Robb Rutledge
Mood disorders are characterized by changes in reaction to positive events, but studies examining mood in gambling have suggested these changes may not be different from control. Interrogating mood changes with a computational model may give insight into disorders like depression.
Psychiatric Risk Gene Cacna1c and Early Life Stress: Potential Gene-Environment interactions?Poster
Early life stress (ELS) is highly associated with development of psychopathology
and mood disorders in adulthood. Genetic studies have identified variation in the gene calcium voltage-gated channel subunit alpha1C (CACNA1C) to increase risk for several psychiatric disorders. This poster assessed the expression of Cacna1c following prepubertal stress.
Regulatory T-Cells (Tregs) Within Bone Marrow-Derived Stem Cells (BMSCs) Actively Confer Immunomodulatory and Neuroprotective Effects Against StrokePoster
We found a distinct subpopulation of Tregs within BMSCs. Tregs and BMSCs in co-culture conferred neuroprotection that varied in a dose-dependent manner. Tregs minimized stem cell production of IL-6, a pro-inflammatory cytokine, and inhibited BMSC secretion of FGF-beta, a cytokine related to BMSC proliferation and differentiation. The ratio of Tregs found natively in BMSCs is optimally adapted to provide the maximum neuroprotective benefit of stem cell treatment after ischemic stroke.READ MORE
Comparing The Anti-Alzheimer's Activity of Different Types of CoffeePoster
This study found that coffee solutions treated at 5% are toxic to neurons. However, the toxicity reduced significantly at 2.5%. While the toxicity was significantly less allowing for more cells to survive at 2.5%, the levels of toxic amyloid beta 1-42 significantly reduced. This reduction in amyloid beta is associated with improvement in cognitive performance, as the presence of these toxic peptides is one of the characteristics of AD pathophysiology.READ MORE
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International Conference on Nanomedicine and Nanotechnology
Aug 20 - Aug 21, 2018