Identifying Non-Intentionally Added Substances (NIAS) in Food Contact Materials
Poster May 24, 2018
Nicola Dreolin, Oliver Burt, Steven Lai, Peter Hancock.
Concern about the safety of food products has increased dramatically with intentionally and non-intentionally added substances (NIAS) used in packaging being of particular interest.
Screening analysis is required to identify chemicals that are present in the packaging. This step usually involves an organic solvent extraction and injection via GC coupled to a quadrupole MS equipped with electron ionization (EI) for volatiles/semi-volatiles as 70 eV scientific libraries are commonly available. However, the identification process requires extensive manual interpretation along with prior technical knowledge when the compound is not listed in the library.
Atmospheric Pressure Gas Chromatography (APGC) is a soft ionization technique enabling the generation of the molecular ion. High resolution MS together with the simultaneous MSE acquisition of molecular and fragment ions generates accurate mass measurements and isotopic pattern and sub-structure information that are all useful in determining elemental composition. APGC and high resolution MS together with a workflow driven process was used to identify unknown compounds in packaging.
Automation of Sample Preparation for Metabolomic Analysis Using Robotic PlatformPoster
We developed an automated sample preparation protocol based on a robotic platform PAL RTC (CTC Analytics AG, Zwingen Switzerland), which represent a modified Bligh and Dyer method producing samples for both hydrophilic metabolomics using GC-MS and lipidomics using SFC-MS simultaneously.READ MORE
Mass Spectrometry: From Imaging to Metabolic NetworksPoster
We show that network analysis of co-localized ions from mass spectrometry imaging data provides a detailed chemo-spatial insight into the metabolic heterogeneity of tumor. Furthermore, module preservation analysis between colorectal cancer patients with and without metastatic recurrence suggests hypotheses on the nature of the different local metabolic pathways.READ MORE
Human exposure to cyanotoxins: Exploring in vitro detoxification using atmospheric cold plasma treatment to protect human healthPoster
Recently, there have been increases in freshwater harmful algal blooms. There is therefore a need to try and effectively detoxify drinking water contaminated with cyanotoxins to safeguard human health by use of new and novel techniques.READ MORE
Comments | 0 ADD COMMENT
10th Annual Congress on Drug Formulation & Analytical Techniques
Sep 03 - Sep 04, 2018