Improved Protein ID and Proteome Coverage with Orbitrap LC-MS
Poster Dec 05, 2019
Aaron M. Robitaille, Tabiwang N. Arrey, Markus Kellmann, Arne Kreutzmann, Daniel Mourad, Daniel Lopez Ferrer, Andreas Huhmer, Alexander Harder
Quantitative proteomics is a powerful tool to study how proteins function or interact with each other in a biological system. Multiplexed quantitation strategies using Thermo Scientific™ Tandem Mass Tags™ (TMT™) enable precise measurement of peptide or protein abundance from multiple samples into a single high-resolution LC-MS analysis.
However, various biological experiments are increasingly demanding higher quantitation accuracy and proteome coverage, which comes with challenges.
Download this poster note to discover how combining technologies can keep up with this demand, improving:
- Protein identification
- Quantification accuracy
- Workflow efficiency