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Applied Biomics, Inc. Adds Global Protein PTM Profiling Service
Product News

Applied Biomics, Inc. Adds Global Protein PTM Profiling Service

Applied Biomics, Inc. Adds Global Protein PTM Profiling Service
Product News

Applied Biomics, Inc. Adds Global Protein PTM Profiling Service


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The company announce the addition of the Global Protein Post-Translational Modification (PTM) Profiling service to its proteomics line. The protein PTMs play a critical role in a wide range of cellular and pathogenesis processes.

The procedure of Protein PTM Profiling involves 2D DIGE followed by quantitative single- or double-color fluorescent 2D Western blot. Proteins with Post-Translational Modifications (PTMs) can be presented in high-resolution 2D images. In addition, the PTM levels in difference samples can be quantified and compared. This service targets the following common Post-Translational Modifications (PTMs):

- Phosphorylation (pSer, pThr, pTyr) - Ubiquitination - Acetylated-Lysine - Tyrosine sulfation - Methyl-Arginine - Nitrotyrosine - Biotinalytion.

The newly added Global Protein PTM Profiling benefits researches in these areas:

1) Identify novel proteins that are post-translationally modified

2) Confirm a specific protein of interest that is post-translationally modified

3) Quantify levels in post-translational modifications among different samples

4) In combination with 2D-DIGE, determine whether differentially expressed protein spots are also post-translationally modified

5) In combination with Mass Spectrometry, determine the site of post-translational modifications

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