Bruker Daltonics Introduces Melamine Food Safety Testing Solution Based on HCT™ Ion Trap Mass Spectrometry
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Bruker Daltonics has released a high-capacity ion trap HCT™ solution for the detection and quantification of melamine and cyanuric acid (CA) by food safety laboratories.
Since September 2008, thousands of infants and young children in China have been hospitalized to treat the symptoms caused by the ingestion of melamine and CA contaminated infant formula and related dairy products. Previously in 2007, pet food, animal feed wheat gluten and other protein-based foods were found to contain residues of melamine and CA.
A five minute LC-MS/MS analysis method has been developed by Bruker Daltonics' food safety development laboratory in Australia. This method for the extraction, detection and quantification of melamine and CA uses quantitative capabilities of the high-capacity ion-trap mass spectrometer HCTultra™, hyphenated with a Dionex UltiMate™ 3000 LC system and Acclaim™ Mixed-Mode WAX-1 column.
The method is capable of detecting melamine in various matrixes well below the concentrations required by various food safety and other regulatory authorities around the world, such as the limits set by the U.S. Food and Drug Administration (FDA) of 1 ppm for melamine and cyanuric acid in infant formula, and 2.5 ppm for other foods.
Dr. Matthias Pelzing, Asia-Pacific Applications Manager for Bruker Daltonics, explained: "We recommend LC-MS/MS methods due to their straight-forward sample preparation, compared to GC-MS methods which often require sample derivatisation. With our new routine analysis method we have demonstrated that melamine can be detected down to trace levels of 0.05 ppb, and that it is possible to quantify melamine at concentrations relevant to various international food authorities in 5 minutes."
Since September 2008, thousands of infants and young children in China have been hospitalized to treat the symptoms caused by the ingestion of melamine and CA contaminated infant formula and related dairy products. Previously in 2007, pet food, animal feed wheat gluten and other protein-based foods were found to contain residues of melamine and CA.
A five minute LC-MS/MS analysis method has been developed by Bruker Daltonics' food safety development laboratory in Australia. This method for the extraction, detection and quantification of melamine and CA uses quantitative capabilities of the high-capacity ion-trap mass spectrometer HCTultra™, hyphenated with a Dionex UltiMate™ 3000 LC system and Acclaim™ Mixed-Mode WAX-1 column.
The method is capable of detecting melamine in various matrixes well below the concentrations required by various food safety and other regulatory authorities around the world, such as the limits set by the U.S. Food and Drug Administration (FDA) of 1 ppm for melamine and cyanuric acid in infant formula, and 2.5 ppm for other foods.
Dr. Matthias Pelzing, Asia-Pacific Applications Manager for Bruker Daltonics, explained: "We recommend LC-MS/MS methods due to their straight-forward sample preparation, compared to GC-MS methods which often require sample derivatisation. With our new routine analysis method we have demonstrated that melamine can be detected down to trace levels of 0.05 ppb, and that it is possible to quantify melamine at concentrations relevant to various international food authorities in 5 minutes."
