NanoSight Announces NanoSight NS500 Nanoparticle Characterization System
Product News Feb 04, 2010
NanoSight has announces the release of the NS500 system. The NS500 incorporates new hardware and software to deliver NanoSight’s growing capability in particle-by-particle characterization in an automated package.
The first system is in use at the University of Oxford in the Nuffield Department of Obstetrics and Gynaecology of the John Radcliffe Hospital as part of a program supported by the Wellcome Foundation.
NanoSight’s technology, known as Nanoparticle Tracking Analysis (NTA), provides a high-resolution particle size distribution, and not by DLS (dynamic light scattering).
NTA detects individual particles as small as 20nm and, in real time, simultaneously tracks and sizes whole populations. The result is a particle size distribution that provides researchers with an over view of their samples showing everything in the whole range 20 - 1,000nm. NTA also provides count and concentration, together with a view which validates these results.
The NS500 adds fluorescence capability, enabling the user to tune into individual particles, with sensitivity to detect individual quantum dots whilst eliminating background interference of other particles and media. Standard beads may be used to bind to single particles for optimum study.
The fluid handling capability of NS500 provides the user with auto sample presentation and in-situ cleaning. It is now a routine process to clean the cell with the ability to purge, flush and load samples through user-customizable software. Dilution may also be optimized then controlled in this way. Ease of use is further enhanced with a motorized focus function to readily home in on the particles under study.
In direct response to user feedback this is augmented with an indexed motorized stage, controlled through the software and providing repeatability in positioning. The temperature control of the cell offers a broad range (15°C to 55°C) and programmable temperature cycling, with rapid attainment of set-point.
The goal of the NS500 is to provide a reproducible platform applicable for specific and general nanoparticle characterization use. So whether the application is to control size in nanoparticle development, provide virus titer or measure the kinetics of protein aggregation, the NS500 system is the solution.