PREMIER Biosoft International has announced the worldwide release of version 2.92 of its MS data analysis tool, SimGlycan®. The program now includes comprehensive support to perform multi-stage/sequential mass spectrometry (MSn) data analysis which involves re-fragmentation of product ions.

Multi-stage mass analysis provides structural information that is useful in structure elucidation of metabolites, glycopeptides and glycans. It aids in discrimination of glycans having similar characteristic fragment ions at MS/MS level. It resolves heterogeneity of carbohydrate distribution and branching pattern of complex glycans such as isobaric isomers.

“Multi-stage mass spectrometry has become a powerful procedure for the investigation of protein glycosylation and therefore, crucial for biopharmaceuticals,” said Kay Brown, V.P. Business Development and Marketing.